Pharmaceutical industry
The latest news relating to the pharmaceuticals industry, including regulation, litigation, business news and relevant industrial and academic research, from the Royal Society of Chemistry's magazine, Chemistry World
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BusinessFatal explosion and fire at Indian pharmaceutical ingredients plant
At least 42 dead and 25 injured at Sigachi Industries near Hyderabad
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BusinessUS approves twice yearly injection to prevent HIV
Yeztugo (lenacapavir) provided near-total protection against infection in clinical trials
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FeatureHibernation awakens interest for drug discovery
With many different species entering torpor for a variety of reasons, scientists are looking to their sleepy secrets for ways to treat human diseases. Anthony King reports
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BusinessSanofi to buy Blueprint Medicines for over $9 billion
Blueprint has one approved drug and enhances Sanofi’s immunology portfolio
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WebinarModelling amorphous solid dispersion (ASD) release mechanisms
Learn how thermodynamic modelling and molecular simulation can help our understanding of amorphous solid dispersion
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OpinionImproving women’s health research will benefit everyone
Fixing the inequality is morally just, and economically sound
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OpinionWomen are not just another confounding factor in drug development
Ignoring physiological differences between the sexes is indefensible
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BusinessTrade deals stave off Trump’s tariffs temporarily
Initial agreements with China and UK have paused trade war, but uncertainty reigns
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OpinionRebuilding pharma supply chains
Multinationals are promising huge US investments, but it’s not all because of Trump’s policies
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OpinionIn search of truth and rules
To codify and predict ever more complex phenomena is one of science’s great drivers
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BusinessMerck KGaA to buy cancer specialist SpringWorks
$3.9 billion deal boosts Merck’s pipeline as it faces patent expiries
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BusinessGilead settles US HIV drug kickback lawsuit
Firm will pay $202 million to federal and state governments
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WhitepaperOptimise drug discovery: predicting transporter-mediated drug interactions
Learn how in vitro models, biomarkers and modelling can improve prediction of drug interactions and toxicity – reducing false positives and unnecessary clinical studies
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BusinessFree energy methods and digital transformation of drug discovery
Synergistic application of AI-based generative chemistry and free energy methods streamlines molecule discovery and optimisation
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OpinionPolymorphs matter – especially when they might disappear
Disappearing polymorphs offer a fascinating example of the dark arts of crystallisation
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NewsFears grow over the future of mRNA vaccine research in the US
Researchers working on mRNA vaccines fear federal funding might be halted, with many looking to move projects abroad
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BusinessAcceptable levels of (epi)genetic engineering
Amplifying or silencing genes may be preferable to permanently changing genetic code
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OpinionThe value of good software extends beyond its cost
Whether third-party or built in-house, thoughtful design and implementation can improve workflows and make science more inclusive
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BusinessGovernment reduces UK Reach fees by ‘£40 million’
Registration fees for most chemicals reduced, but uncertainty remains over safety data requirements
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BusinessEpigenetic editors enter clinical trials
New wave of precision medicines amplify or silence genes, without altering genetic code