All articles by Andy Extance – Page 2
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FeatureThe promise of drugs that send proteins to the shredder
Andy Extance charts how research into revolutionary targeted protein degradation therapies is moving from serendipity to strategic discovery
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ResearchGPT-based AI tool predicts inorganic crystal structures
CrystaLLM uses GPT to arrange atoms, turning text-based data into numerical tokens
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FeatureA mouthful of mouthfeel
Andy Extance learns how the chemicals in food and drink create sensual culinary experiences
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ResearchVisible light-powered catalysts clean up ‘forever chemicals’
Organic photoredox catalysts show promise for fluorinated pollutants
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FeatureClearing up the compostable plastic mess
Rather than a potential triumph, the compostable plastics we use look increasingly like a tragedy. Andy Extance looks at the problems and seeks solutions
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ResearchProteins with multiple structures open up AlphaFold’s black box
AI prediction model often fails to identify fold-switching, helping show how it works and the limits of its usefulness
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FeatureHow satellite remote sensing is enhancing our understanding of Earth
Instruments in space have studied the planet’s atmosphere and surface, and are now being joined by powerful new ones, finds Andy Extance
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BusinessMDMA rejection poses questions for psychedelic drug trials
Decision prompts reflection over how psychotherapy is involved, regulating combination treatments and safeguarding patients
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ResearchAI tool outperforms existing x-ray structure methods
Deep learning approach determines phase of diffracted beams with lower-quality data
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FeatureHow a new strategy aims to break the catalytic speed limit
The Sabatier principle normally defines the maximum reaction rate enabled by catalyst materials, but scientists now think that they can go even faster, explains Andy Extance
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ResearchThe catalyst speedup toolkit
A rundown of the various strategies scientists are exploring to cheat the Sabatier limit
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NewsHow can your lab cut water use in reflux reactions?
Practical advice builds on a new study comparing air-cooled condensers
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FeatureWhy don’t we know how antidepressants work yet?
Selective serotonin reuptake inhibitors are at the centre of a collision between social and biochemical outlooks on depression, finds Andy Extance
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FeatureBrain chemistry basics
Andy Extance looks into the latest in Alzheimer’s disease, pain and memory
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ResearchElectronic cooling device is part fridge, part muscle
Soft polymer material flexes to move heat between surfaces
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ResearchScreening reveals thousands of ‘undrugged, yet druggable’ proteins
Collaboration involving Pfizer develops freely accessible AI tool to probe protein–compound interactions
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ResearchFirst mirror-image cyclodextrins come together ‘like Lego’
L-enantiomers could be more stable than their existing, more common, forms
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ResearchCarbon’s allotrope explosion demonstrates how the element is both versatile and fickle
New all carbon materials are relatively easy to predict but challenging, if not impossible to make, experts tell Andy Extance
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ResearchPulsating chemical computers vie with their quantum rivals
The Belousov-Zhabotinsky reaction powers cellular automata and optimisation calculations
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ResearchKinky findings drive crystal growth paradigm shift claim
How molecules attach chemically at surfaces can be more important than how strongly solvents bind them in determining growth rate