All articles by Andy Extance – Page 3
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NewsUS accelerator accident hospitalises worker, delays XFEL startup
The SLAC National Accelerator Laboratory lab director has stood down after the latest in a series of safety incidents and complaints
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BusinessMerck & Co identifies nitrosamine source in diabetes drugs
Investigation uncovers the cause of contamination in sitagliptin medicines, but the wider nitrosamine problem is ballooning
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ResearchAI model accurately classifies reaction mechanisms
Machine learning ‘surpasses chemist experts’ in identifying chemical processes
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FeatureThe brain chemicals that control what we enjoy
Researchers are trying to understand how orexins influence our appetites, and whether we can use them to treat addiction and obesity, explains Andy Extance
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FeatureHow a murder and a bombing cleaned up DNA profiling
The UK pioneered a forensic process to identify suspects from tiny amounts of DNA, but occasional flaws had big consequences. Andy Extance pieces together the whole story for the first time
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FeatureLife’s chemistry goes through the looking glass
Chemists were taught that natural systems only use L-amino acids. Andy Extance finds out just how wrong that is proving
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ResearchVibrational reactivity control harnesses quantum realm to speed up chemistry
‘Quantum phase control’ supercharges reaction between chlorine and singly deuterated methane at ambient temperature
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ResearchUnusual hydrogen bonds found in proteins help them bind their targets
Weak interactions between hydrogen and carbon atoms have synthetic chemistry implications
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BusinessPatent office cements priority for Crispr gene editing in cells
Nobel laureates’ failed challenge means companies may need extra patent licenses
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ResearchVibrational spectroscopy distinguishes different diffusing isotopes
Scanning transmission electron microscopy-based method tracks graphene growth with atomic precision
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ResearchIBM teaches reaction planning system to ‘speak enzyme’
RXN seeks to use enzyme catalysis to make chemistry more sustainable and resource efficient
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ResearchSwimming molecules come under intense scrutiny
Discoverers of enhanced diffusion in click cycloaddition reactions stand firm after other groups say they can’t reproduce the findings
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FeatureHow ammonia could decarbonise shipping
Andy Extance discovers why the compound best known as a fertiliser is a surprising candidate to power enormous container ships
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FeatureHow a virus ancestor powers our memory’s chemistry
Andy Extance tells the astonishing story of the Arc protein and its capsid forms, and the questions it poses
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ResearchNeural network scours vast chemical space to design drug-delivering peptides
Oligonucleotide drug activity boosted 50-fold with peptide designed by machine learning algorithm
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NewsMachine learning delivers ‘human genome’ moment for proteins
Protein structure prediction tools AlphaFold and RoseTTAFold take the latest steps towards maturity and make their software open source
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ResearchElectrochemical DNA on a chip sensor detects bacterial urinary tract infections faster
Synthetic nucleic acid probes combine with tiny star-shaped electrodes tests for bacteria in less than an hour
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NewsScientists build case for a UK x-ray laser more advanced than any in the world
Support sought for facility with higher quality, shorter pulses, to begin operation after 2030
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FeatureComputer-guided retrosynthesis
Machine learning-based systems hope to outperform expert-guided reaction planning technology, finds Andy Extance
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ResearchNitrogen deletion reaction offers ‘new way to think about molecular editing’
Reagent inspired by decades-old research could save chemists a lot of headache when it comes to modifying molecules’ skeleton