All Drug formulation and delivery articles
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NewsFirst malaria vaccine approved as hopes raised for new, better ones
Mosquirix prevents just 30% of severe malaria cases in young children prompting a guarded welcome
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Research
Programmable peptoid template for disrupting protein–protein interactions inside cells
System optimises residues involved in binding target independently from those that promote membrane permeability
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Research
Neural network scours vast chemical space to design drug-delivering peptides
Oligonucleotide drug activity boosted 50-fold with peptide designed by machine learning algorithm
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Business
Developing countries sidelined in Covid-19 vaccine scramble
Lack of funds and local manufacturing capacity has prevented Covax from competing with wealthier nations’ self-interest
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Business
Sartan contaminant recall hits generics manufacturers
Three European suppliers recalling multiple batches of medicines owing to active ingredient contamination
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Research
Pollen-mimicking antidote saves bees after pesticide exposure
Calcium carbonate microparticles deliver detoxifying enzyme to bees’ guts
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Research
Click chemistry uses endogenous acrolein to activate cancer prodrug
Strategy could reduce chemotherapy side effects by selecting for cancerous cells
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Research
Ingestible COF that delivers insulin could help diabetics duck injections
When blood glucose levels are high, glucose displaces insulin loaded in the framework
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Business
Antibody–drug conjugates drive growth in oncology
Antibody–drug conjugates are coming of age and pharma is investing, reports Katrina Megget
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Opinion
Why are impurity regulations different for food and drugs?
The pharmaceutical and food industries should work together more closely on genotoxic impurities
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Business
University team’s silica coats stop vaccines spoiling at room temperature
Asel Sartbaeva hopes her pioneering ensilication technology will be adopted to store and transport pediatric vaccines to low-income countries
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Sponsored
AstraZeneca puts academia at the heart of pharma
At the heart of chemical biology are the molecules that make medicines effective and safe for consumers. AstraZeneca harnesses the scientists at the heart of academia to create a healthier world
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News
Oxford University to open antimicrobial research centre after £100m donation from Ineos
Petrochemical giant highlights dangers of antibiotic resistance
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Business
Pharmaceuticals roundup 2020
Alongside the race for Covid-19 treatments and vaccines, the industry has maintained momentum
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Research
Animal tests reveal synthetic decoy protein protects against coronavirus
Protein designed from scratch binds Sars-CoV-2 with high affinity and specificity
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Sponsored
Faster pharma: Catalytic innovation combats precious metals supply chain pain
Precious metal catalysts are key to pharma but subject to market forces that make reliance on supply a double-edged sword.
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Sponsored
AI and digital simulation for better medicines, made faster
Revolutionising pharma with next-generation technology to optimise and accelerate drug production processes
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Research
Fast-acting insecticide polymorph could boost malaria-control efforts
Recrystallised deltamethrin accelerates uptake in mosquitoes
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Research
Salt bridge strategy expands access to pharmaceutical cocrystals
New approach to cocrystallisation could lead to exciting multi-drug combinations
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Opinion
Questioning European policy on alkyl mesylate impurities
Policies based on false hypotheses can persist in spite of overwhelming contradictory data
