All Drug formulation and delivery articles
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Research
Antibiotic adjuvant designed to subvert bacterial defence mechanisms
Amphiphilic molecule helps obsolete antibiotics accumulate and act within bacteria
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Opinion
Compounding problems
Regulating the line between a vital service and grey-market profiteering is a mess
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Research
New insights into polyamorphism could influence how drugs are formulated
Findings suggest dihedral angle distribution might explain why polyamorphs have different physical properties
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Business
UK becomes first country in the world to authorise a Crispr-based gene therapy
Treatment aims to cure patients with β-thalassaemia and sickle-cell disease
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Research
Insulin medicines more resilient to temperature than previously thought
Review suggests more lenient storage guidelines could make diabetes treatments more accessible
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Business
Tornado at Pfizer plant accentuates US drug shortage issues
Perennial problem will not be addressed without major reforms to drug market
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Article
Light-activated molecular motor drives drug delivery
Drug-delivery system is a ‘step towards using molecular motors in the clinic’
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Opinion
Bringing drug manufacturing back home
Pharmaceutical supply chains are international, complex and opaque. Is there a better way?
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News
Air jet gun delivers needle-free vaccines in MOFs without any need for refrigeration
Release rate of injector system can be fine-tuned by changing the carrier gas
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Research
The hunt is on for vaccine ingredients that don’t come from wild sharks
Yeast can provide the raw materials and chemical wizardry can transform them
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Business
Encoding creativity in drug discovery
Machine learning can complement and reinforce human intuition and experience
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Sponsored
Thermal analysis in the development of long-acting injectable systems
Evaluating new polymers for slow-release drug delivery could deliver better treatment for patients
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Feature
Tiny delivery systems for cancer drugs
Encapsulating anticancer agents in nanoparticles can make them gentler on the rest of the body. Clare Sansom reports
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Business
An evolution in pharma outsourcing
Contract services firms are becoming increasingly sophisticated and embedded in the ecosystem of drug development
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News
Software from Cambridge crystallographic experts could save pharma industry millions
Informatic tools will help drug formulators understand particle behaviour in their final product
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Opinion
May cause side effects
The dose makes the poison, but understanding unwanted drug interactions is complicated
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Research
Light-activated cancer treatment uses tumour-targeting enzymes to cut side effects
Enzymatic activation of a photosensitive prodrug in cancerous cells shows promise in mice
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Business
What is the future of Covid-19 pharmaceuticals?
Firms anticipate long-term markets for prevention and treatment
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Research
Edible, fluorescent silk tags could help stem tide of counterfeit medicines
Marker could be a simple answer to ensuring provenance of drugs
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Business
Moderna sued over Covid-19 vaccine-related patents
Arbutus and Genevant say lipid nanoparticles that protect mRNA infringe six key patents