All Drug formulation and delivery articles – Page 4
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Business
Sartan drug contamination brings cancer uncertainty
Levels of nitrosamines and other carcinogens in affected tablets of valsartan and related drugs similar to smoking 20 cigarettes a day
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News
X-ray crystallographer to oversee Rosalind Franklin Institute
Structural biologist James Naismith to become first director of UK’s new national life sciences institute
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Business
Breaking the silence of RNA interference drugs
A wave of treatments is set to follow the first approval of an RNAi therapy
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Research
Scorpion venom peptide engineered to sting brain disorders
Structure used to escort nanoparticles across blood–brain barrier also resists protease degradation
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Podcast
Furanocoumarin
Florence Schechter discovers how a seemingly healthy grapefruit-based breakfast could disrupt your daily drugs
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Research
First oral antibiotic booster for four decades could tackle drug resistance
Sulfate-masking strategy makes bacterial enzyme inhibitor an easy pill to swallow
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News
New life sciences institute wants to make drug discovery 10 times more efficient
The UK’s £103 million Rosalind Franklin Institute will unite robotics, chemistry and biophysics to generate drug candidates within weeks
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Sponsored
Are polymer medicines viable therapeutics?
Combining small-molecule medicines with polymers could offer big rewards for pharmaceutical researchers
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Feature
3D printing in pharma
Nina Notman explores how 3D printing is carving out a niche for itself in the pharmaceutical industry
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Opinion
Why combination pills aren’t always the answer
The challenges of medicines containing multiple drugs aren’t going away
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Business
Fit for repurpose
Drugs that can be used for new indications offer a potentially cheaper pathway – but only if the investors can recoup their costs
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Sponsored
Is industry ready for the serialisation shake-up?
The regulation few outside of pharma have heard about
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Sponsored
Driving pharmaceutical innovation
Making drugs is neither easy nor cheap – but catalysts, flow chemistry and a knowledge of intermolecular interactions can help
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Sponsored
Dissolving insoluble drugs
How spray drying can help with solubility and bioavailability challenges in drug development
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Feature
The chemistry of the microbiome
Our gut bacteria are carrying out chemistry on our behalf, but without us knowing much about it. Now, scientists are starting to examine their enzymes
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News
Illegal antibiotic combinations threaten efforts to battle antimicrobial resistance
Unapproved formulations make up two-thirds of combination therapies sold in India
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Feature
Artificial blood
Nina Notman reports on progress towards products that can, when necessary, replace donor red blood cells
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Business
Drug formula change infuriates French thyroid patients
Poor communication of changes to Merck KGaA’s levothyroxine has led to complaints of side effects
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Research
Responsive nanoparticles target sight-stealing fungus
Eye drop tricks fungal eye infection into self-destruction
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Feature
Delivering gene therapy
After some well-publicised problems, gene therapy – delivering DNA into people’s cells using viruses – is booming, Anthony King finds