Medicinal chemistry – Page 3
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WebinarThe science and promise of liquid biopsies: improving cancer treatment
Learn how liquid biopsies are being used to identify cancer and improve patient outcomes
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OpinionA chemist in the flower garden
The beautifully complex molecules plants produce are as inspiring as the blooms themselves
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FeatureBlood biopsies for cancer
Testing small amounts of blood for the presence of disease markers could revolutionise how we detect cancer. Clare Sansom reports
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ResearchYellow food dye could give doctors a new way to look beneath the skin
Tartrazine can safely and reversibly turn the skin of mice transparent
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BusinessTea tree oil faces ban in UK and EU over reprotoxicity
Defenders question relevance of animal safety data that triggered decision
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BusinessUS industry braced for change as election looms
Regulation, trade tariffs and innovation support top lists of concerns
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OpinionBeing wrong is almost inevitable
On the tightrope of expressing your opinion, you always risk looking a fool
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OpinionGLP-1 drugs could be more than a win–win for weight loss
Semaglutide and tirzepatide are changing lives, and could change our attitudes
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FeatureThe GLP-1 weight loss revolution
Glucagon-like peptide-1 agonist drugs, such as semaglutide, could save countless lives at risk due to diabetes and obesity. Rachel Brazil looks at the difficulties in making the peptides themselves, and what’s coming next
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OpinionProteins’ shape and function are two sides of the same coin
A new perspective on the relationship between chemistry and biology
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BusinessMDMA rejection poses questions for psychedelic drug trials
Decision prompts reflection over how psychotherapy is involved, regulating combination treatments and safeguarding patients
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ResearchPotential new class of antibiotics takes on flesh-eating infections
Peptide-mimicking compounds target bacterial cell walls
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ResearchInnovative antibacterial strategy shows promise for treating infections
New antibiotic mechanism sees molecule infiltrate bacterial cells and destroy them from the inside
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ResearchAnalytical chemistry tools point to the future of personalised medical diagnostics
Molecular fingerprinting techniques outperform standard blood tests for detecting the onset of many diseases
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OpinionMedicinal chemistry’s biological blind spots
Despite advances in modern medicine, there are some big gaps in our knowledge
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ResearchTherapeutic proteins can hitch a ride on parasite to bypass blood-brain barrier
Toxoplasma could be delivery agent for protein drugs – provided parasite can be made safe
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BusinessWeight-loss drugmakers bet billions on boosting supplies
Eli Lilly and Novo Nordisk invest to expand in-house manufacturing of GLP-1 drugs
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ResearchDrugs and vaccines could be freed from cold chains by hydrogel
Stiff gel prevents proteins from aggregating, preserving their therapeutic power
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ResearchNanopore proteins designed from scratch and turned into biosensors
Artificial ion channels used to detect disease indicators and pharmaceuticals