All Medicinal chemistry articles – Page 9
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OpinionSolving the technetium medical isotope shortage
The UK has a solution to the potential shortage of technetium-99m – but that’s no reason to be complacent about leaving Euratom
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Opinion
Make room for randomness in drug development
Setting free the dark horses sometimes beats the most rational planning
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Webinar
Current topics in bioconjugation
Insights into making bioconjugates using optimal reagents and the latest techniques to create highly active and stable complexes
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Podcast
Indometacin
A popular prescription pill that helps to keep gout and other arthritic conditions under control
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Business
Bristol-Myers Squibb bags immunotherapy unicorn
Deal will add to pharma giant’s cancer portfolio
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Research
Plotting a course to new antibiotics
Mapping out the chemical space of peptide antibiotics offers an efficient way to find new compounds
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Opinion
(+)-Pleuromutilin
Total synthesis is sometimes the only way to explore the chemical space around a natural product
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Research
Simplified structure eases antibiotic synthesis
New analogues of the potent antibiotic teixobactin could be instrumental in the fight against multi-drug resistant pathogens
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Opinion
Making enough of a difference
What if the needle in the drug development haystack ends up being too small to be useful?
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Business
FDA approves first sickle cell drug in almost two decades
Glutamine-based drug is the first approved for children over 5
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Business
Amplifying intelligent drug design
This year’s Chemistry World Entrepreneur of the year is Andrew Hopkins of start-up Exscientia and the University of Dundee, UK
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Research
Bismuth drug structure solved
After over three centuries of mystery, the structure of bismuth subgallate has finally been uncovered
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Podcast
Caesium chloride
A compound found in mineral water that is also used in medical treatments and solar cells
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Opinion
Unpicking a clinical trial death
A new study shows up off-target effects of a drug that proved deadly, and highlights the pitfalls of drug discovery
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Podcast
Fibrin and fibrinogen
From scabby knees to life-threatening strokes, this important protein is the fundamental link in the complex molecular chain that forms blood clots
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Podcast
Propranolol hydrochloride
Stave off stage fright with a simple compound that revolutionised drug development
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Research
How total synthesis is creating antibiotics
Macrolide synthesis could reinvigorate the antibiotic pipeline
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News
News from the American Chemical Society meeting in San Francisco
News stories from the 253rd National Meeting & Exposition of the American Chemical Society
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Research
Maple syrup enhances antibiotics
A phenol-rich mixture extracted from maple syrup allows much smaller doses of antibacterial drugs to achieve the same results
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News
How we are fighting tropical diseases
Repellents and vaccines are useful but still need further improvement
