All Medicinal chemistry articles – Page 2
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ResearchRetrosynthetic algorithm broadened to design similar, but different, molecules
Chematica can now design efficient syntheses for large compound libraries
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Podcast
Amygdalin & Laetrile
Patrick Hughes delves into the molecule at the centre of a decades-old cancer treatment conspiracy theory
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News
Data manipulation casts shadows on Novartis gene therapy
Manufacturing problems with other new medicines highlight difficulty of developing advanced treatments
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Opinion
Margaret Brimble: 'Spiroketals are my favourite molecules'
The New Zealand chemist on careers, creativity and why everything just has to be blue
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Opinion
Are new drugs better than existing ones?
Should companies be made to change the way they run clinical trials?
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Research
Modified metallohelices show medical potential
Post-assembly click reactions on helical metal complexes produces biological activity akin to that of the arrow poison ouabain
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Sponsored
Multidisciplinary science kick starts innovation
Nanoform scientists discuss how their diverse personalities and scientific backgrounds foster innovation, helping them tackle problems from different angles, and design better processes
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Podcast
Zinc polycarboxylate
Lay back in the chair and say 'Ahh', as Mike Freemantle introduces zinc polycarboxylate dental cement
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Research
Bacterial lasso gets to the heart of stem cell retention problem
A sticky bacterial protein on the surface of stem cells increases homing and retention on damaged heart tissue
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Opinion
The silent rise of the robots
Mechanical helpers have been creeping into our labs for decades
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Podcast
Cyclopropane
Chemistry’s tastiest bonds for an explosive anaesthetic that was as useful as it was dangerous
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Podcast
2C psychedelics
A class of hallucinogenic phenethylamines, explored by the 'godfather of psychedelics' Alexander Shulgin and sadly implicated in a tragedy at a 2017 music festival
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Research
Colourful antibiotics isolated from scorpion venom
Isolated benzoquinone has excellent activity against TB along with low toxicity in mice
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News
Northwestern opens largest biomedical building of any US university
Chemistry sits atop Northwestern University’s new 12-story interdisciplinary biomedical centre
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Research
Glucose-regulating nanogel keeps blood sugar in the sweet spot
System prevents hyperglycemia in rats by acting like an artificial liver
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Opinion
Is this a golden age of new drug classes?
A host of new treatment modes are hitting the clinic and the market
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Research
Spore shell acts as sunscreen for light-sensitive antibiotics
Polymer capsule that protects and preserves antimicrobial compound could aid fight against multi-drug resistant pathogens
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Research
Laser technique watches how implants release drugs
Laser induced breakdown spectroscopy continues to diversify its applications
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Webinar
Miniaturise the haystack: DNA-Encoded Libraries for drug discovery
A DNA-Encoded Library (DEL) case study and fragment-based DEL discovery insight from DyNAbind
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Business
US finalises guidance on biosimilars
Regulator clarifies requirements for allowing substitution between products
