All Medicinal chemistry articles – Page 2
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NewsUS children’s hospital takes delivery of one of world’s most powerful NMR spectrometers
Instrument offers unprecedented opportunities to study disease development
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Review
Mescaline: A Global History of the First Psychedelic
A story about the people who harvested, used, abused, regulated and investigated the mind-altering drug
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Feature
Stem cell hype
Many clinics around the world offer unproven treatments, while genuine therapies are slowly making their way through trials. Anthony King reports
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Podcast
Boric acid
Mike Freemantle revisits battlefield surgery to investigate boric acid, a key part of Dakin's antiseptic solution used extensively in the first world war
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Research
Retrosynthetic algorithm broadened to design similar, but different, molecules
Chematica can now design efficient syntheses for large compound libraries
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Podcast
Amygdalin & Laetrile
Patrick Hughes delves into the molecule at the centre of a decades-old cancer treatment conspiracy theory
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News
Data manipulation casts shadows on Novartis gene therapy
Manufacturing problems with other new medicines highlight difficulty of developing advanced treatments
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Opinion
Margaret Brimble: 'Spiroketals are my favourite molecules'
The New Zealand chemist on careers, creativity and why everything just has to be blue
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Opinion
Are new drugs better than existing ones?
Should companies be made to change the way they run clinical trials?
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Research
Modified metallohelices show medical potential
Post-assembly click reactions on helical metal complexes produces biological activity akin to that of the arrow poison ouabain
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Sponsored
Multidisciplinary science kick starts innovation
Nanoform scientists discuss how their diverse personalities and scientific backgrounds foster innovation, helping them tackle problems from different angles, and design better processes
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Podcast
Zinc polycarboxylate
Lay back in the chair and say 'Ahh', as Mike Freemantle introduces zinc polycarboxylate dental cement
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Research
Bacterial lasso gets to the heart of stem cell retention problem
A sticky bacterial protein on the surface of stem cells increases homing and retention on damaged heart tissue
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Opinion
The silent rise of the robots
Mechanical helpers have been creeping into our labs for decades
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Podcast
Cyclopropane
Chemistry’s tastiest bonds for an explosive anaesthetic that was as useful as it was dangerous
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Podcast
2C psychedelics
A class of hallucinogenic phenethylamines, explored by the 'godfather of psychedelics' Alexander Shulgin and sadly implicated in a tragedy at a 2017 music festival
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Research
Colourful antibiotics isolated from scorpion venom
Isolated benzoquinone has excellent activity against TB along with low toxicity in mice
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News
Northwestern opens largest biomedical building of any US university
Chemistry sits atop Northwestern University’s new 12-story interdisciplinary biomedical centre
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Research
Glucose-regulating nanogel keeps blood sugar in the sweet spot
System prevents hyperglycemia in rats by acting like an artificial liver
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Opinion
Is this a golden age of new drug classes?
A host of new treatment modes are hitting the clinic and the market
