Medicinal chemistry – Page 2
-
BusinessPfizer and Novo Nordisk’s battle over Metsera
Lawsuits fly in bidding war over developer of next generation weight loss drugs
-
ResearchNanobodies from alpacas and llamas could hold the key to a universal antivenom
Novel nanobody mix protects against 17 African snake species
-
BusinessNovartis spends on deals to offset patent losses
$12 billion Avidity acquisition is the latest pipeline-pumping transaction
-
ResearchThis fragment-based drug discovery library is designed to be sociable
Study targets a key bottleneck in hit to lead optimisation by designing fragments that are both structurally diverse and easy to elaborate
-
WebinarSYNTHIA for chemists: faster route design
Discover how SYNTHIA accelerates retrosynthesis by helping chemists design, compare and refine routes with customisable filters and commercial building blocks
-
Business23 Indian children’s deaths linked to contaminated cough syrup
Dietheylene glycol contamination highlights consequences of poor inspection and enforcement
-
ResearchUltrapotent thrombin inhibitor combines peptide fragments from a trio of blood-sucking organisms
Hybrid molecule featuring leech, tsetse fly and flea peptide fragments binds thrombin at three sites
-
WebinarDeveloping a CITK protein degrader using the QuicTPD™ platform
Learn about the latest technology to accelerate the design of cancer treatments
-
OpinionKeeping tabs on contamination
Argentina’s contaminated fentanyl tragedy highlights challenges of generic drug supply
-
BusinessArvinas and Pfizer seek a new home for protein degrader drug
Companies offer bifunctional cancer drug vepdegestrant to new partners after disappointing trial results
-
BusinessNovo Nordisk’s new chief cuts 9000 jobs
Danish firm shifts strategy after struggling to capitalise on its weight loss drugs
-
ResearchGut bacterium amplifies amphetamine’s addictive pull
Discovery could lead to better ways to treat addiction
-
OpinionIs UK pharma really ‘uninvestable’?
Merck & Co, AstraZeneca (AZ) and Eli Lilly pulling UK projects highlights the precarious position of the country’s life sciences industry
-
BusinessUK loses life sciences investment as pharma companies halt expansion plans
Industry seeks greater share of healthcare spending to support innovation
-
WebinarIon suppression correction and normalisation in metabolomics
Join us to learn new ways to improve data consistency with mass spectrometry
-
OpinionLiver toxicity remains an unpredictable hurdle for medicinal chemists
The liver’s complex role in metabolising drugs makes it both a critical consideration and potential stumbling block
-
OpinionDeadly fentanyl contamination exposes drug safety challenges
Bacterial contamination in medical fentanyl has killed at least 51 people in Argentina, highlighting pressures on generic drugmakers
-
WebinarLipidomics for antibiotic resistance (AMR) mechanisms
Discover how microbial antibiotic exposure triggers lipidomic changes, offering insight into how lipids contribute to resistance mechanisms
-
ResearchScientists capture crystal structures of cannabinoid receptor in action
Study reveals how two aromatic residues flip when agonists bind, providing the trigger for downstream signalling
-
CareersTeaching the next generation of cosmetic scientists
Trailblazing course receives accreditation from the Royal Society of Chemistry