All Medicinal chemistry articles – Page 10
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ResearchPutting the ‘ant’ in antibiotics
Antibacterial polyketides uncovered in the most unusual of places
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Research
Molecular structure is teixobactin’s pièce de résistance
Study builds scientists’ arsenal against drug-resistant superbugs
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News
Alzheimer’s disease: have drug developers been on the wrong track?
Dementia drug developers urged to look beyond amyloid
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Podcast
Adamantane
Brian Clegg introduces a crystalline hydrocarbon that isn’t as tough as it sounds, but is the basis of a wide range of medicines
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Business
Taming vaccines with chemistry
Vaxxilon aims to simplify vaccine development by replacing biological components with well-defined synthetic molecules
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Research
Roadkill: new molecules at the side of the road
Wild animals run down on the roads can open surprising doors for opportunistic biochemists
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Feature
New opioid drugs
Creating powerful new painkillers is a constant battle against side-effects – particularly addictions. James Mitchell Crow reports
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Feature
Intracellular delivery
Drugs that can enter cells and take useful payloads with them are maturing, finds Andy Extance
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Opinion
How much does fashion influence chemists?
Is that new reaction the next Nobel-worthy breakthrough, or just a flash in the pan?
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Podcast
Bromodeoxyuridine
Kat Arney illuminates the story of a molecular ‘highlighter pen’ for growing cells
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Opinion
Restarting the mental health pipeline
The lack of UK investment in new drugs for mental health disorders is a problem – but the tide may be about to turn
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Careers
The trials and tribulations of drug discovery
The many pitfalls medicinal chemists face when creating a new drug
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Podcast
Benzoyl peroxide
The blondest blonde, the whitest smile, the clearest complexion – all from one essential compound
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Research
Dibrominated tag helps identify new natural products
New substance allows researchers to find new aldehyde- and ketone-containing natural products
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Podcast
PARP: Poly (ADP-ribose) polymerase
Kat Arney explains how a protein that repairs broken DNA holds the key to killing cancer cells – but only if you stop it from doing its job
