Medicinal chemistry – Page 10
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ResearchAmide library created at speed with machine learning and stopped-flow chemistry
Approach used 90% less starting material than continuous flow equivalent
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FeatureTiny delivery systems for cancer drugs
Encapsulating anticancer agents in nanoparticles can make them gentler on the rest of the body. Clare Sansom reports
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OpinionNobel vision
Looking beyond the here-and-now let click chemistry open up a whole new world of possibility
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BusinessAlzheimer’s antibody engenders anticipation
Tantalising press-released data on Biogen and Eisai’s lecanemab prompt questions without firm answers
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BusinessAn evolution in pharma outsourcing
Contract services firms are becoming increasingly sophisticated and embedded in the ecosystem of drug development
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OpinionThe end of a long race?
The finishing line of the Covid-19 pandemic may be in sight, but we mustn’t stop running just yet
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FeatureCan we clean Covid from the air around us?
Nina Notman talks to the experts about what is needed to remove pollutants and even infectious diseases from the air inside our homes, schools and offices
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OpinionContribute to defeating malaria
The Medicines for Malaria Venture needs new compounds for screening and more chemists to join its open-souce drug discovery project
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Feature50 years of artemisinin
Jamie Durrani tells the story of how a wonder drug against malaria was discovered from a plant in a secret Chinese military project
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NewsFrench inquiry censures lab that promoted hydroxychloroquine to treat Covid
Report raises awkward questions about prominent study on antimalarial conducted in Didier Raoult’s lab
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ResearchYeast engineered to ferment sugars into chemotherapy drug precursors
Semisynthesis offers new route to anticancer drug vinblastine
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BusinessArrayit chief convicted of fraud over blood testing
Mark Schena misrepresented the company’s value to investors and defrauded public and private insurers
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OpinionConfusing cannabinoids
Decomposition during GC–MS analysis can thwart efforts to determine if a product is legal
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WebinarHow to profit from recent innovations in small molecule drug discovery
Reduce risk, cost and wasted time in the new era of small molecule drug discovery
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WebinarFinding new medicines for malaria
Join Chemistry World for this interactive webinar and explore some of the collaborative avenues of research looking for new medicines to prevent and treat one of our oldest foes.
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ResearchArtificially evolved enzyme tackles tricky cross coupling
Directed evolution on the metalloenzyme cytochrome P450 creates a catalyst for making macrocyclic antibiotics
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BusinessJ&J to phase out talc-based baby powder worldwide
In the face of thousands of lawsuits, firm will switch to cornstarch-based formulations
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ResearchCombining expertise to develop remote-controlled nanomaterials
Beatriz Pelaz explains how her research tackles bionanomaterials from multiple angles
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BusinessProtective treatment for Covid-19 makes minimal impact
Limited uptake of antibody combination for vulnerable patients, while demand for antivirals seems to be slowing