Organic chemistry – Page 4
-
ResearchSupramolecular gels improve performance of aircraft deicing fluids
Made using low-cost reagents, the gels could be more sustainable than current anti-icing products
-
ResearchAI continues to make waves and structural editing impresses in 2025
The research that has amazed and amused us this year
-
ResearchProbability model guides synthesis of interwoven catenane structure
Organic cage-like compounds selectively form intricate structure during one-pot synthesis
-
WhitepaperOptimise cross-coupling with ligand-free NHC–Pd precatalysts
Discover how new NHC–Pd precatalysts deliver superior performance without stabilising ligands
-
ResearchParamagnetic NMR used to probe covalent character of halogen bonds
Assessing hyperfine shifts in paramagnetic NMR spectra provides new details on the covalent character of halogen bonded cocrystals
-
ResearchStable nitrogen chiral centres are possible – under the right conditions
Chiral nitrogen compounds might one day be used as reagents, catalysts or even as drugs
-
OpinionA robotic helping hand
Mechanical labmates are making huge progress, but there are still big challenges to overcome
-
ResearchModular strategy opens up new way to synthesise arylated thiophene rings
Approach holds potential for creating new drugs and unique optoelectronic materials
-
ResearchInfrared and NMR fusion boosts automated structure verification
Study highlights untapped potential of IR spectroscopy data
-
ResearchA current take on the Swern oxidation
Electrochemical update to a classic reaction trades cryogenic conditions for room temperature, to selectively convert primary and secondary alcohols into aldehydes and ketones
-
NewsUK’s new national laboratories site will support ‘invisible infrastructure’ of measurements that keep world in sync
£20 million investment by LGC will boost country’s analytical and metrology capabilities
-
Opinion(−)-Novofumigatonin
Oxidations abound in this satisfying synthesis, with a delicate nitrile hydrolysis to finish
-
ResearchQuantum tunnelling drives aromaticity flip-flop
Augmented pentalene structure could be a molecular Schrödinger’s cat, aromatic and antiaromatic at the same time
-
ResearchThis fragment-based drug discovery library is designed to be sociable
Study targets a key bottleneck in hit to lead optimisation by designing fragments that are both structurally diverse and easy to elaborate
-
ResearchAll stirred up: chemical engineers refute claims that ‘stirring doesn’t matter’
Failing to mix reactions in heterogeneous or industrial systems could cause numerous issues and might even be dangerous, preprint claims
-
ResearchDihydropyrazine-embedded macrocycles behave like supersized cycloalkanes
Giant molecular rings that mimic the puckered shapes of cyclobutane, cyclopentane and cyclohexane could offer new insights into conformational dynamics
-
Research‘Stimulating discovery’ leads to strategy to swap oxygen in saturated rings
Skeletal editing pushed beyond aromatic structures, sparking new opportunities in drug discovery
-
WebinarSYNTHIA for chemists: faster route design
Discover how SYNTHIA accelerates retrosynthesis by helping chemists design, compare and refine routes with customisable filters and commercial building blocks
-
OpinionMy arcane and curious connection to metal-organic frameworks
Fernando Gomollón-Bel uncovers a link between his hometown and the 2025 Nobel prize in chemistry
-
NewsMeet the three scientists who have just won the Nobel prize in chemistry
Learn about the lives of newly minted chemistry Nobel laureates Susumu Kitagawa, Richard Robson and Omar Yaghi