Biology and biotechnology
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Research
First regular molecular fractal in nature
Scientists have identified a protein that has a fractal structure and find that it was simply an evolutionary accident
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Research
Screening reveals thousands of ‘undrugged, yet druggable’ proteins
Collaboration involving Pfizer develops freely accessible AI tool to probe protein–compound interactions
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Research
Study raises questions about media used for in vitro tests on nanomaterials
Multiomics profiling details how biomolecular corona that form in conventional cell culture differ to those that form in human plasma
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Research
New mechanism identified that is potentially linked to very early stages of Alzheimer’s
Understanding role of fragments of amyloid protein could lead to novel therapies for the disease
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Research
E. coli engineered to become methanol addict to make industry feedstocks
Bacterium could head off food versus fuel dilemma by producing chemicals from agricultural waste
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Research
Microscopy structures reveal mechanism behind bitter taste
Cryo-EM images provide a detailed picture of bitter taste receptors
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Research
Self-dyeing vegan leather made by genetically engineered bacteria
Material can be shaped into shoes and wallets, offering a sustainable alternative to traditional leather
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Research
Microplastics passed on during cell division
New research sheds light on the influence of microplastics on cellular processes
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Research
Deep learning algorithm predicts structures of biomolecular assemblies
RoseTTAFold extended to predict structures of proteins bound to small molecules
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Research
Enzyme engineering makes blue denim greener
Environmentally friendlier alternative to indigo dye can now be made at a competitive price
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Research
Striking reptilian fossil discovered in 1931 found to be fake
280-million-year-old lizard ‘fossil’ was mostly painted on
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Research
Blueberries’ blue is just skin deep, depending on structure not pigments
Non-spherical nanostructures explain the fruit’s colour
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Research
Human decomposition driven by unique community of microbes
Findings could help crime scene investigators determine time of death
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Research
Engineered enzymes break down silicon–carbon bonds in siloxane, an emerging pollutant
Directed evolution offers a way to tackle waste silicone
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Research
Violent volcanic lightning created the nitrogen compounds essential for the chemistry that led to life
First direct evidence of nitrates linked to eruptions discovered
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Research
Heavy metals are potential ovarian toxicants
Exposure to metals like arsenic, cadmium and mercury linked to reduced egg production, earlier menopause for middle-aged women
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Research
Unravelling enzyme pathway of Taxol precursor brings synthetic production of cancer medicine closer
Expression of nine genes in tobacco plants led to formation of complex precursor of drug
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Research
E. coli rewired to shift carbon flow towards C4 chemicals
Bioengineering strategy creates evolutionary advantage linking cell growth with product formation
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Research
PFAS linked to foetal metabolism disorders
‘Forever chemicals’ in the livers of unborn children can alter lipid metabolism and may increase the risk of metabolic disease in adulthood