Pepto-Bismol compound’s structure unveiled after 120 years
Electron microscopy triumphed over x-ray crystallography as century-old structural puzzle around bismuth subsalicylate is finally solved
Discovery of microplastics in people raises difficult questions about health implications
Scientists keep finding tiny polymer particles in lungs, blood and placentas – but what does that mean means for people’s health?
Sea sponges own unique chemistry goes beyond that of their bacterial guests
Biologically potent compounds can be made by sea sponges themselves
Epigenetic MRI offers a way to understand how the brain learns
First tests in humans could be as little as year away, researchers claim
Reprogrammed bacterium turns carbon dioxide into chemicals on industrial scale
Process achieved at industrial scale in 120 litre reactor
Electric field of ATP synthase suggests enzyme has functions beyond catalysis
Study links energy-making enzyme with proton migration in ATP formation, and reinforces predictions that its catalytic efficiency is around 90%
Cancer progression and harmful bacteria tracked with next-generation sequencing
Proof-of-principle study keeps an eye on leukaemia mutations and bacterial strains in patients
Life’s handedness could have arisen spontaneously on Earth
New insight into the origins of homochirality point to adaptation to energy sources as driver
AI-engineered enzyme eats entire plastic containers
Enzyme with only five amino acid alterations depolymerises 51 different PET products faster and at lower temperature than other proteins
Yeast engineered to convert methanol into heparin
Production levels are currently low, but researchers hope the method could one day mean pharma doesn’t have to rely on animals for this essential medicine
Sulfonated macrocycle helps the medicine go down
A supramolecular approach makes alkaloid drugs taste less bitter
Biochemical secrets of tarantula’s painful bite could point to perfect painkillers
King baboon spider venom could help scientists develop potent analgesics
New microscope makes tracking chiral molecules in live cells possible
The instrument uses circularly polarised light to tell left- and right-handed species apart and monitor them in space and time
![Terphen[3]arene](https://d2cbg94ubxgsnp.cloudfront.net/Pictures/415x277/7/3/6/518736_d2cc00040gf1_733670.jpg)
3D printing adds another dimension
The incredible antibodies of sharks, llamas and camels
The human health observatory in our sewers
Life’s chemistry goes through the looking glass
A decade of CAR-T cell therapy
The curious case of the ancient brain
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Array of compounds found in plastics promote fat cell formation in vitro
A third of thousands of chemicals that leach from consumer polymers linked to the development of fat cells
Heavy oil-eating microbe grown in lab for the first time
Archaeon that breaks down long alkanes into methane and carbon dioxide could be used for energy recovery from depleted oil reservoirs
Engineered antibody that snags sperm could be an effective non-hormonal contraceptive
Approach could offer new method of contraception for women
Prokaryotes programmed to produce paracetamol avoid pervasive petrochemicals
Genetically modified E. coli serve as green factories for painkillers
Gel-forming proteins could help tardigrades survive extreme conditions
Biophysical dissection of tardigrade’s disordered protein could uncover how microscopic animals survive conditions that kill most other forms of life
First carbon-making microbes discovered
Mysterious black material produced by deep sea archaea and bacteria found to be carbon
Gallium helps sneak antibiotic payload into bacterial cells
Compound is more potent than parent drug ciprofloxacin against Staphylococcus aureus
Glassware found to promote reactions in Miller–Urey 'primordial soup' experiment
By running their famous 1952 experiment in glass flasks, Stanley Miller and Harold Urey might have unintentionally simulated the role of rocks on early Earth
Individual proteins identified with world’s tiniest ruler
Nanosized caliper that can identify individual proteins could ‘do for proteins what next-generation sequencing did for DNA’
Possible dinosaur DNA discovered in 125-million-year-old fossil
But that doesn’t mean we can clone extinct species Jurassic Park-style
Tiny shear forces have big effect on protein reactions
Proteins react faster under the forces they experience when they squeeze through blood vessels