Enzyme evolved that can perform reactions new to nature
New possibilities for organic synthesis with enzymatic C–H functionalisation
Synthetic molecules fold up into abiotic proteins
Compound that self-assembles into giant folded ring could help scientists design bespoke abiotic proteins
Blood pressure drug reacts with membrane lipids
Lipidation products add to evidence that biological membranes are far from chemically inert
Nanodecoys lure and trap Zika virus
Gelatin nanoparticles camouflaged by mosquito membrane mop up virus and stop it crossing placenta
DNA sugar could form on icy asteroids and comets
Water–methanol ices bombarded with UV simulate conditions found on comets and asteroids
Pore-forming toxins detect long strands of DNA
Lithium electrolyte helps aerolysin overcome electrostatic obstacle to detect ssDNA longer than 100 nucleotides
Two flavouring chemicals prevalent in e-cigarettes might harm lung function
Diacetyl and 2,3-pentanedione suppress gene expression related to cilia production and function
Alzheimer’s linked to infection of the brain by gum disease bacterium
Drug firm is developing treatment to inhibit bacterial enzymes believed to be damaging important protein
Cooking chemistry has a taste for making glue
Adhesive made from soy with Maillard reaction could replace formaldehyde glue in furniture
Screening strategy pursues photocatalytic couplings for drug discovery
High-throughput screening and flow-based scale-up combo identifies chemistry needed to functionalise drug fragments and obtain useful amounts of product
Liquid analysis simultaneously checks for 71 elements
Technique delivers elemental fingerprint of everything from water to wine in minutes
Self-powered cancer therapy triple whammy
Diagnosis, drug delivery and effectiveness monitoring combination could realise precision cancer therapy
Weird mechanism behind catnip compound’s biosynthesis uncovered
Nepetalactone – the compound cats go crazy for – is made by a two-step procedure that is unlike any other in terpenoid biosynthesis
Pass the antidote
Can we live forever?
Ready for a Raman shift
A taste of wine chemistry
The marvellous Maillard reaction
How chemical evolution took the 2018 chemistry Nobel prize
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Double umpolung approach to amino amide synthesis
Unusual disconnection strategy behind stereocontrolled route to β-amino amides
Suspicions of bacteria’s role in rotting wood finally proven
Bacteria have been thought to be involved in breaking down lignin for 40 years but evidence has been hard to come by
Surface chemistry for biological questions
Rasmita Raval discusses her career exploring the complex behaviour of molecule–surface systems and what it has to do with antibiotic resistance and the origin of life
Wearable sensor checks blood alcohol content using sweat
Device shows how sweat could be used as a non-invasive source of biochemical information
Forensic volatile analysis estimates age of bodily fluids
In situ analysis identifies blood, urine and saliva whilst discriminating against common interferents
‘Chirality gene’ puts life in a twist
Simple molecular interactions may underpin the asymmetry of biological systems
Mass spec goes massive weighing huge virus particles
Nanomechanical system can weigh protein complexes and viruses more than 100MDa in mass
Venom peptides reveal secrets of scorpion evolution
The shapes of toxins found in venom are helping to resolve the scorpion’s family tree
Scorpion venom peptide engineered to sting brain disorders
Structure used to escort nanoparticles across blood–brain barrier also resists protease degradation
Drug precursor made by solar-powered cyborg yeast
Indium phosphide nanoparticles supply electrons for shikimic acid synthesis
Catalytic fix for nitrogen fixation
Single-atom ruthenium catalyst doubles efficiency of electrochemical reduction of nitrogen to ammonia
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