Machine learning accurately predicts RNA structures using tiny dataset
Development could lead to better understanding of RNA and new medicines
Overreliance on cryocooled protein structures may compromise computational structure-based drug design
Scientists behind first of its kind study encourage more researchers to analyse protein structures at room temperature
Water splitting electrocatalyst made from unconventional alloy containing 14 elements
Simple dealloying process creates complex nanoporous alloy
Chemical definition of brine as water could help clear up Chile’s lithium controversy
As evidence grows that lithium mining damages water sources, reclassifying brine as water – rather than as mineral – could empower Indigenous communities to protect their rights and convince mining companies to act more responsibly
Electrons in zinc’s filled 3d orbitals can participate in chemical reactions
Super electrophilic trianions accept three additional electrons to support zinc in a +3 oxidation state
Hardest amorphous material can scratch even diamond
Compressing buckyballs at high temperatures makes ultra-hard and strong carbon materials
Liquid crystals under pressure create squid-like camouflage
Pneumatic membranes trigger full-spectrum colour shifting on demand
Method to make unusual oligonucleotides could be a boon for gene therapy drugs
Synthesis can insert unusual linkages into DNA molecules while rivalling industry standard chemistry in speed and efficiency
Giant molecular cage protects plastic-eating enzyme
Caged protein withstands temperatures much hotter than its usual melting point and becomes 1000 times more resistant to solvents
First fluoronium crystal solves structure controversy
X-ray analysis of elusive cation finally proves it to be a symmetric near-covalent structure, not a carbocation
Semimetal study links spiral magnetism to Weyl fermions
Findings may help explain spatial modulations seen in the magnetism of other rare earth intermetallic compounds
How a single ingredient creates silky smooth chocolate without tempering
Natural phospholipids trigger cocoa butter crystallisation into glossy, tasty, melt-in-the-mouth chocolate
Actinide aromaticity defies predictions
First σ-aromatic thorium cluster extends σ aromaticity to periodic table’s heaviest elements
How the power of smell could identify new medical tests
The search for the grand unification of aromaticity
Supermetals versus superbugs
The rise of ferrofluids
Computer-guided retrosynthesis
Drink, drugs and disease: the chemistry of breath tests
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Blue light squeezes out heteroatoms from small rings
Photochemical ring editing reaction allows complete molecular shape change in a single step
First crystal structure of bleach in its 200-year history
X-ray structure of chemistry staples hypochlorite and hypobromite recorded for the first time
Tusk isotopes reveal a mammoth’s life
17,000 years after its death, scientists use strontium analysis to trace animal’s movements throughout its 28-year life
This smartwatch will self-destruct in 40 hours
Electronic waste recycling made easy with this dissolvable device
Gold(III) catalysis transforms protecting group from base-stable to base-labile
Unique orthogonality in a protecting group achieved using a gold-catalysed cyclisation for selective activation and deprotection
Transient quantum fluctuations tune polymer self-assembly
Chemists use to the universe’s random electromagnetic fluctuations to profoundly change a compound’s supramolecular organisation
Molecular cryo-EM discovers error in 25-year-old natural product structure
Nobel prize-winning biomolecule imaging technique adapted to characterise chemical compounds faster and easier than NMR and x-ray
Photocatalyst couples denitrification and water splitting to manage nitrate pollution
Hydrogen gas generated in situ serves as reducing agent
Mirror image enzyme constructs longest ever mirror DNA strand
Since chirally inverted DNA is more stable than its natural counterpart, it can be used to encode secret messages
Giant crystal lattice is mesoporous but not a MOF
Non-covalent network has the largest unit cell among non-MOFs
There was more than simple oxygen depletion to ancient mass extinction event
Thallium isotopes reveal that rapid swings in ocean oxygenation preceded the events that wiped out 90% of species 250 million years ago