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ResearchEnigmatic DNA dubbed ‘Borgs’ discovered in methane-metabolising microbes
The large nucleic acid structures may help bacteria play a role in regulating global methane
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Research
Snake extract used to speed up haemostasis in new bioadhesive
Hydrogel-based bioadhesive could be suitable for arterial injuries
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Research
Individual cell’s energy metabolism caught on camera for the first time
Combining machine learning with fluorescence imaging provides new insight in glycolysis and might help with development of new therapies for cancer
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Article
Kathleen Culhane Lathbury – an industrial pioneer
Nina Notman tells the story of the interwar industrial chemist whose analytical skill and persistence saw her outmanoeuvre sexism and prove her research aptitude
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Business
Non-animal test for skin sensitisation gets OECD approval
Combination strategy developed by BASF and Givaudan is the first complete replacement for animal testing
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Business
Engineering microbes to degrade contaminants
Allonnia is using synthetic biology to tackle major environmental challenges like PFASs, metals and plastic waste
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Research
Electrochemical DNA on a chip sensor detects bacterial urinary tract infections faster
Synthetic nucleic acid probes combine with tiny star-shaped electrodes tests for bacteria in less than an hour
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Research
Molecular machines talk to living cells for the first time
Artificial molecular motors gently pull on cells’ membrane receptors to trigger a biochemical response
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Opinion
Opening up a cellular black box
Working out how biomolecular condensates work may reveal a lot about the success or failure of different drugs
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Business
Sartan contaminant recall hits generics manufacturers
Three European suppliers recalling multiple batches of medicines owing to active ingredient contamination
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Article
Mabel FitzGerald and the mystery of oxygen sensing
Katharine Sanderson celebrates the tenacious and brilliant researcher who came tantalizingly close to describing oxygen sensing, a concept that earned the Nobel prize over 100 years later
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Research
Quantum chemical reaction behind birds’ internal compass
Can migratory robins ‘see’ Earth’s magnetic field at night?
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News
Race to understand Sars-CoV-2 variants amid fears virus might evade vaccines
Biochemical basis behind coronavirus variants’ success could hold key to defeating them
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Business
BMS and Eisai agree antibody-drug conjugate commercialisation deal
Companies will jointly develop cancer treatment, with BMS paying up to $3 billion for shared rights
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Research
Sortase A strategy could see ribosomal products reach further across chemical space
Compound libraries set to benefit from process that harnesses promiscuity of post-translation enzymes
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Feature
Supermetals versus superbugs
With pathogenic bacteria rapidly overcoming our arsenal of organic antibiotics, James Mitchell Crow asks if it is time to revisit metal-based antimicrobials
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Business
Regeneron’s Covid-19 antibodies help those who can’t make their own
Regn-Cov2 reduces deaths and shortens hospitalisation for these patients, even when given at late stages of infection
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Research
Blocking bacteria’s self-poisoning mechanism weakens their antibiotic resistance
Stopping bacteria from producing hydrogen sulfide in response to drugs could help overcome antimicrobial resistance
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Business
Alzheimer’s antibody gets surprise US approval
Good news for industry and future drug approvals, but physicians doubt it will be effective for most patients
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Research
Biochemical mystery unfolds as elemental metals found in Alzheimer’s patients’ brains
In a discovery that raises more question than it answers, researchers have found zero-oxidation-state iron and copper deposits inside amyloid plaques
