Medicinal chemistry – Page 14
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Article
Unlocking the future of medicines manufacturing with digital innovations
The Medicines Manufacturing Innovation Centre promises to revolutionise how we formulate, trial and produce medicines
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Business
Antibody–drug conjugates drive growth in oncology
Antibody–drug conjugates are coming of age and pharma is investing, reports Katrina Megget
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Opinion
How the pandemic might change drug research
Derek Lowe muses on some positive lessons learned
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Business
Why manufacturing Covid vaccines at scale is hard
Exploring the pinch points vaccine makers face as they ramp up production
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Research
Molecular pendulum sensors could track and monitor disease
DNA–antibody probes can detect specific proteins inside a live subject
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Opinion
Why are impurity regulations different for food and drugs?
The pharmaceutical and food industries should work together more closely on genotoxic impurities
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Feature
Flow chemistry surges forward
The long-discussed technique could help make pharma manufacturing more distributed, finds Andy Extance, and create opportunities for chemists with the right skills
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Review
The Doctor Who Fooled the World: Andrew Wakefield’s War on Vaccines
The story of the man who created the myth that a vaccine causes autism
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Business
University team’s silica coats stop vaccines spoiling at room temperature
Asel Sartbaeva hopes her pioneering ensilication technology will be adopted to store and transport pediatric vaccines to low-income countries
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News
Green light for world’s first Sars-CoV-2 studies that will infect healthy volunteers
UK trials will assess how well Covid-19 treatments work and if vaccines protect against new virus variants
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Business
Coronavirus variants stymie success of monoclonal antibodies
Lab-made antibodies can treat and protect people from Covid-19 but are more likely to succeed when administered as a cocktail
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Feature
Drugging RNA
Some medicinal chemists have changed their focus from proteins to target RNA, finds Rachel Brazil
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Webinar
Physics-based computational modeling applied to the design and optimisation of biologics
Explore how FEP technology (including FEP+) can be applied in protein engineering work
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Review
The Poison Trials: Wonder Drugs, Experiment, and the Battle for Authority in Renaissance Science
An extremely well-researched monograph containing stories that bear an eerie resemblance to today’s politicised clinical trials
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Research
Linking chemistry with surgery to detect cancerous cells in situ
Livia Schiavinato Eberlin explains how her team has developed a hand-held device for surgeons that analyses tissue samples on a mass spectrometer mid-operation
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Opinion
A rough guide to pharma partnership deals
Coronavirus vaccines are driving unusual collaborations with a range of benefits
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Business
Biggest venture yet of any pharma company into cannabis
Jazz Pharmaceuticals buys cannabinoid therapeutic firm for $7.2 billion, inheriting first plant-derived cannabinoid medicine ever approved by FDA
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Business
Covid vaccination efforts bolstered by trial results from J&J and Novavax
A miserable January ended with positive news on the vaccine front but new variants added complications
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Article
AstraZeneca puts academia at the heart of pharma
At the heart of chemical biology are the molecules that make medicines effective and safe for consumers. AstraZeneca harnesses the scientists at the heart of academia to create a healthier world