Join us on 5 November to learn new ways to improve data consistency with mass spectrometry

Event details and registration

Register now

Ion suppression is a major problem in mass spectrometry (MS)-based metabolomics. It occurs when the signal intensity of an analytical sample is reduced due to the presence of other compounds in the sample matrix. Consequentially, there can be dramatic decreases in measurement accuracy, precision, and sensitivity.

Join us on 5 November for a live, interactive webinar, in which our expert guests will demonstrate how the IROA TruQuant Workflow can correct ion suppression and normalise data by using a library of stable isotope-labeled internal standards (IROA-IS). These standards act as known reference points within the sample, while companion algorithms use these references to detect and fix where ion suppression is occurring, as well as normalising MS metabolomic data to make results more consistent across samples. 

By attending this webinar, you will:

  • Understand the errors that affect quantitative accuracy and statistical relevance in metabolomics
  • Learn how to use the TruQuant workflow to correct these errors
  • Discover practical applications in metabolomic research, illustrating how this TruQuant helps in workflows to deliver more reliable and consistent data

To aid accessibility, automatically generated closed captions, which can be turned on and off at your leisure, will be available to all those attending live. Please note, a certificate of attendance will be provided soon after the event. You do not need to request this; only those who attend the webinar live will be eligible.

Felice de Jong

Portrait of Felice de Jong

Felice A. de Jong is founder and chief executive officer of IROA Technologies. She earned her doctorate in molecular biology and biochemistry from the University of Melbourne, Australia, and has held leadership roles at Boehringer Mannheim (Roche), Sigma-Aldrich Australia, and Sigma-Aldrich’s neurobiology subsidiary, RBI, in Boston.

An early advocate for metabolomics, de Jong advanced Metabolon’s growth through strategic partnerships and market development. At IROA Technologies, she leads the development of products that enable accurate identification and reproducible quantitation of metabolites.

 

Karnakar Reddy Chitta

Portrait of Karnakar Reddy Chitta

Karnakar R. Chitta is a global product manager at MilliporeSigma, the life science business of Merck KGaA, Darmstadt, Germany. He holds a PhD in chemistry from the University of Cincinnati, Ohio, and an MBA from the University of Missouri–St. Louis, Missouri.

He began his career at MilliporeSigma as a senior scientist, spending seven years in research and development and quality control before moving into product management. In his current role, he manages a broad portfolio of chemical products, including vitamins and coenzymes, signaling and modulation tools, glycobiology reagents, and metabolite libraries, with a focus on advancing glycomics and metabolomics research.

Event details and registration

Register now

Merck KGaA leads innovation across life science, healthcare, and electronics, advancing medicine, enabling manufacturing, and powering smart technology globally. The Life Science business of Merck operates as MilliporeSigma in the U.S. and Canada.View full profile

More Merck KGaA

Topics