All Medicinal chemistry articles
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ResearchTri-agonist molecule designed to stimulate immune system crosstalk
Conjugation chemistry connects three different agonists around a triazine core
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Webinar
Molecular modeling for the medicinal chemistry toolkit
Join us on May 27 to discover how to streamline your workflows using integrated software solutions for docking, ligand design, and optimisation
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Research
Ingestible COF that delivers insulin could help diabetics duck injections
When blood glucose levels are high, glucose displaces insulin loaded in the framework
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Research
Machine learning tool sets out to find new antimicrobial peptides
IBM researchers say their fully automated AI-driven system could speed up the discovery of molecules for novel antibiotics
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Sponsored
Digital technologies in the personalised medicines revolution
The revolution will be digitalised
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Sponsored
Unlocking the future of medicines manufacturing with digital innovations
The Medicines Manufacturing Innovation Centre promises to revolutionise how we formulate, trial and produce medicines
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Business
Antibody–drug conjugates drive growth in oncology
Antibody–drug conjugates are coming of age and pharma is investing, reports Katrina Megget
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Feature
Flow chemistry surges forward
The long-discussed technique could help make pharma manufacturing more distributed, finds Andy Extance, and create opportunities for chemists with the right skills
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Business
University team’s silica coats stop vaccines spoiling at room temperature
Asel Sartbaeva hopes her pioneering ensilication technology will be adopted to store and transport pediatric vaccines to low-income countries
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Business
Coronavirus variants stymie success of monoclonal antibodies
Lab-made antibodies can treat and protect people from Covid-19 but are more likely to succeed when administered as a cocktail
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Feature
Drugging RNA
Some medicinal chemists have changed their focus from proteins to target RNA, finds Rachel Brazil
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Business
Biggest venture yet of any pharma company into cannabis
Jazz Pharmaceuticals buys cannabinoid therapeutic firm for $7.2 billion, inheriting first plant-derived cannabinoid medicine ever approved by FDA
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Business
Covid vaccination efforts bolstered by trial results from J&J and Novavax
A miserable January ended with positive news on the vaccine front but new variants added complications
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News
Oxford University to open antimicrobial research centre after £100m donation from Ineos
Petrochemical giant highlights dangers of antibiotic resistance
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News
Decoding the virus – what we know about Sars-CoV-2 a year on
Scientists have never learnt so much about a pathogen in such a short time
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Research
Nitrogen radical chemistry sees the light
Daniele Leonori explains how his group is taking inspiration from 30-year-old chemistry to devise shorter syntheses for bioactive compounds
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Business
Vaccine approvals offer hope as global Covid cases surge
A handful of vaccines are now approved and the first doses are being given to patients, with trials for many more candidates nearing completion
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Business
Pharmaceuticals roundup 2020
Alongside the race for Covid-19 treatments and vaccines, the industry has maintained momentum
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Research
Chemists tame shamanic addiction treatment
Animal experiments show modified structures remove ibogaine’s hallucinogenic and heart-harming effects
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Feature
2020: the year the world changed
Andy Extance discovers how scientists around the world have responded to the pandemic, working on solutions from drugs and vaccines to hand sanitiser and PPE
