Medicinal chemistry
The latest chemistry news and research on medicinal chemistry including drug discovery, clinical trials, toxicology and science of disease, from the Royal Society of Chemistry's magazine, Chemistry World
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BusinessWill oral weight loss drugs challenge injectables?
Pills may offer convenience for manufacturers, but it’s not clear they will overtake existing drugs
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BusinessThe challenge of developing oral alternatives to peptide weight loss drugs
Companies are racing to develop alternatives to injectable diabetes and weight loss drugs
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NewsWhat are the top journals in chemistry right now?
Following the recent release of journal impact factors, we round up the leading journals across 10 chemistry fields
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NewsUS government cancels mRNA vaccine research
Experts fear industrial and academic research may move abroad after infectious disease projects cancelled
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ResearchLow lithium levels linked to Alzheimer’s
Immune cells’ ability to degrade amyloid-beta peptides restored in mice treated with lithium salt
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Opinion‘Creative destruction’ in the chemistry lab
Some obsolete lab equipment is quickly replaced, while other items are stubbornly persistent. What modern tech will survive to the 2060s?
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BusinessMerck & Co to cut 6000 jobs, Moderna to cut around 500
Both firms aiming to make significant reductions in annual costs by reorganising
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ResearchAI tools turned to creating designer proteins for personalised cancer therapies and antibiotics
Powerful new class of AI model could dramatically speed up process of producing new kinds of drug candidates
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NewsAs AI-designed drug looks to pass final hurdle, will this tech change drug discovery forever?
AI-led drug for chronic lung disease set to enter phase 3 clinical trials, though experts remain divided on AI’s impact in pharma
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OpinionLearning about chemistry in prenatal class
Opportunities for infographics to contribute to health literacy
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OpinionChina’s drug development charge
Reforms and state support have fuelled domestic and foreign investment in pharmaceutical
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ResearchMorphine analogues kill pain with fewer negative side effects
Redesign of the potent painkiller’s core prevents breathing suppression and reduces addiction-related behaviours in mice
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WebinarWomen’s health: insights in research and inclusion
Learn about the history and importance of the gender gap currently impacting women’s health sciences – Join us on 28 August
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NewsWhy is a prehistoric creature still vital for the pharmaceutical industry?
Every year, horseshoe crabs are harvested for their blue blood, but alternatives are now coming through that could help protect these ancient animals
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ResearchDNA barcodes can make drug discovery screens miss potential medicines
Flawed data is likely compromising machine learning methods
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BusinessUS approves twice yearly injection to prevent HIV
Yeztugo (lenacapavir) provided near-total protection against infection in clinical trials
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FeatureHibernation awakens interest for drug discovery
With many different species entering torpor for a variety of reasons, scientists are looking to their sleepy secrets for ways to treat human diseases. Anthony King reports
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BusinessSanofi to buy Blueprint Medicines for over $9 billion
Blueprint has one approved drug and enhances Sanofi’s immunology portfolio
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OpinionNon-hallucinogenic psychedelics
Chemical insights and advances are contributing to a new therapeutic avenue for mental health conditions
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ResearchAFM maps the way collagen unfolds and refolds in the body
New insights could aid understanding of connective tissue disorders