Medicinal chemistry
The latest chemistry news and research on medicinal chemistry including drug discovery, clinical trials, toxicology and science of disease, from the Royal Society of Chemistry's magazine, Chemistry World
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OpinionPolicies for advanced wound care dressings in India
India faces a growing crisis in wound treatment, driven by diabetes and an ageing population. A new policy approach could enable Indian innovation to meet this need.
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OpinionPhotodynamic and sonodynamic therapies for anticancer and antibacterial applications
These emerging treatments require a supportive regulatory and policy approach
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WebinarTaking the sting out of pain: how marine venoms can be used to heal
Join us on 24 April to learn how marine venoms are being used to treat chronic pain
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OpinionModerna’s vaccine regulatory hokey-cokey
US FDA initially refused to accept flu vaccine for review, but has since reversed that decision
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WebinarHigh‑throughput retrosynthesis for real‑world chemistry
Join us on 24 March to discover how retrosynthesis software, paired with application programming interfaces, can accelerate route design, virtual screening and practical synthesis decisions
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NewsExplainer: What is epibatidine?
The science behind the dart frog toxin that was allegedly used to kill the Russian politician Alexei Navalny
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PodcastAlphaGenome & the RNA world hypothesis
In this episode, we discuss Google DeepMind’s latest deep learning model AlphaGenome, dissect the origins of life from chemicals to complex lifeforms, and hear the latest headlines.
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ResearchWorld first for clinical trial of skin patch to monitor therapeutic drugs in real time
Sensor could soon help doctors to prevent overdoses of drugs
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OpinionIs it cold in here?
Labs in Delhi, Aberdeen and Arizona will have different ideas of ‘room temperature’
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NewsIn 2023, the UK was the first country to approve a Crispr therapy. How’s it doing?
Disconnect exists between the media hype around gene-editing treatment and the reality for patients
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OpinionCrispr therapies will change medicine but there will be challenges along the way
The first treatments making use of Crispr gene editing may suffer some early hiccups
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FeatureThe toxic chemistry behind skin bleaching products
The global skin-lightening market is worth over $10 billion and growing, but the unregulated products driving it contain dangerous chemicals linked to serious health risks. Zahra Khan speaks to the scientists and advocates trying to fix the problem
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ResearchAI tool dramatically reduces computing power needed to find protein-binding molecules
New protocol is up to 10 million times faster than current docking-based methods
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NewsNew £50 million centre aims to shake up clinical trials in the UK
Initiative should speed up testing of new medicines
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OpinionAn airborne exposure route for a serious kidney disease
Linking Aristolochia plants to aristolochic acid nephropathy
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ResearchCrystal structure prediction reaches new heights with axitinib
Computational strategy predicts complex polymorphs and distinguishes salts from co-crystals
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BusinessUK agrees higher drug prices to secure zero-tariff deal with US
NHS could pay up to 25% more for innovative drugs, but exports will be tariff free for three years
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OpinionWhat’s on your lab technology wish list?
Once-magical tools are now mundane. What will the next miracles be?
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ResearchRevived claims that antibiotics don’t kill bacteria with reactive oxygen prove controversial
Researchers say that multiple lines of evidence for hypothesis have now been undermined
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OpinionInhaler propellant switch is worth the effort
Memories of a year spent testing new inhaler valve designs