Medicinal chemistry
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NewsPersonalised medicine has failed to live up to the hype, researchers claim
Predictions that Human Genome Project would usher in an era of tailored therapies have largely failed to come true
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OpinionHow teenagers are disrupting drug discovery
A citizen science project to improve access to malaria drugs
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ResearchAlzheimer’s linked to infection of the brain by gum disease bacterium
Drug firm is developing treatment to inhibit bacterial enzymes believed to be damaging important protein
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ResearchScreening strategy pursues photocatalytic couplings for drug discovery
High-throughput screening and flow-based scale-up combo identifies chemistry needed to functionalise drug fragments and obtain useful amounts of product
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ResearchPatent-busting AI tool navigates around protected drug pathways
Organic retrosynthesis software can identify key bonds involved in patented reactions to find alternative pathways
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OpinionWhat are the rate-limiting steps in drug discovery?
Getting more drugs to market is not just a chemistry problem
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ResearchCrowdsourced drug discovery pits half-forgotten compounds against neglected diseases
45 research groups donate 350 compounds to the first crowdsourced screening library
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PodcastEllagic acid
Louise Crane introduces the antioxidant that led to exaggerated claims that 'whisky helps fight cancer'
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ResearchBlood pressure drug reacts with membrane lipids
Lipidation products add to evidence that biological membranes are far from chemically inert
