All Drug discovery and development articles
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OpinionContribute to defeating malaria
The Medicines for Malaria Venture needs new compounds for screening and more chemists to join its open-souce drug discovery project
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Feature
50 years of artemisinin
Jamie Durrani tells the story of how a wonder drug against malaria was discovered from a plant in a secret Chinese military project
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Research
Yeast engineered to ferment sugars into chemotherapy drug precursors
Semisynthesis offers new route to anticancer drug vinblastine
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Webinar
How to profit from recent innovations in small molecule drug discovery
Reduce risk, cost and wasted time in the new era of small molecule drug discovery – join us on 29 September
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Webinar
Finding new medicines for malaria
Join Chemistry World in this interactive webinar and explore some of the collaborative avenues of research looking for new medicines to prevent and treat one of our oldest foes.
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Business
Protective treatment for Covid-19 makes minimal impact
Limited uptake of antibody combination for vulnerable patients, while demand for antivirals seems to be slowing
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Opinion
Why AlphaFold won’t revolutionise drug discovery
Protein structure prediction is a hard problem, but even harder ones remain
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Opinion
May cause side effects
The dose makes the poison, but understanding unwanted drug interactions is complicated
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Business
California advances plans to make its own insulin
Governor commits $100 million to develop low-cost insulin and build manufacturing facility to strengthen drug’s supply chain
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Opinion
Alzheimer’s, amyloid and abandoned antibodies
Biogen’s aducanumab is stumbling into obscurity. Where does that leave the amyloid hypothesis?
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News
New questions raised over Sputnik Covid vaccine results point to fraudulent practices
Analysis comparing Sputnik results with five other Covid vaccines finds phase 3 trial outcome is highly improbable
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Research
Breaking bacteria’s genetic silence to synthesise antibiotics that evade resistance
Prospecting in bacterial genomes offers hope in search for new antimicrobial drugs
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Business
What is the future of Covid-19 pharmaceuticals?
Firms anticipate long-term markets for prevention and treatment
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Feature
The incredible antibodies of sharks, llamas and camels
Sharks and llamas share a strange quirk of their immune systems. Hayley Bennett finds out how their ‘nanobodies’ could help us tackle Covid and a host of other diseases
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Research
AI tool finds green ways to turn chemical waste into drugs
Circular approach for industry by-products considers environmental, economic and geographic aspects to rank predicted routes for real-world applications
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Webinar
Speed up process development by making more from your offline and online data
Learn how the biotechnology R&D team at Clariant uses statistical modelling techniques to speed up the process development of their bio-ethanol product
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Business
UK takes subscription approach for new antibiotics
Decoupling payment from prescriptions helps preserve last-line antibiotics and encourage R&D
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Feature
A decade of CAR-T cell therapy
Nina Notman looks at the revolutionary treatment already taking on cancer, now aiming for wider use
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News
Drug discovery AI that developed new nerve agents raises difficult questions
Researchers shocked by how easily algorithm discovered novel poisons even deadlier than VX
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Opinion
A spanner in the works
Most drugs work by breaking or stopping something, rather than by making something faster or better
