Drug discovery and development
The latest chemistry news and research on drug discovery and development, including cancer drugs, antibiotics, vaccines and drug screening, from the Royal Society of Chemistry's magazine, Chemistry World
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OpinionIndia’s generic semaglutide surge
As patents on Novo Nordisk’s diabetes and weight loss blockbusters expire, generic makers have their versions ready
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FeatureNew treatments offer hope for neglected snakebite victims
Nina Notman meets the scientists developing recombinant antivenoms and small molecule inhibitors to save the lives and limbs of snakebite patients, who number in the their hundreds of thousands
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BusinessBoron plays a key role in new sleeping sickness drug
Acoziborole is the first single-dose treatment for both early and late stage sleeping sickness
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FeatureCone snail venom peptides offer new hope for pain relief
Cone snails deploy sophisticated venom cocktails to paralyse prey. Anthony King talks to the researchers harnessing these peptides to develop new pain medications
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WebinarTaking the sting out of pain: how marine venoms can be used to heal
Join us on 24 April to learn how marine venoms are being used to treat chronic pain
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OpinionModerna’s vaccine regulatory hokey-cokey
US FDA initially refused to accept flu vaccine for review, but has since reversed that decision
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WebinarHigh‑throughput retrosynthesis for real‑world chemistry
Discover how retrosynthesis software, paired with application programming interfaces, can accelerate route design, virtual screening and practical synthesis decisions
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OpinionIs it cold in here?
Labs in Delhi, Aberdeen and Arizona will have different ideas of ‘room temperature’
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OpinionCrispr therapies will change medicine but there will be challenges along the way
The first treatments making use of Crispr gene editing may suffer some early hiccups
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ResearchAI tool dramatically reduces computing power needed to find protein-binding molecules
New protocol is up to 10 million times faster than current docking-based methods
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ResearchCrystal structure prediction reaches new heights with axitinib
Computational strategy predicts complex polymorphs and distinguishes salts from co-crystals
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BusinessUK agrees higher drug prices to secure zero-tariff deal with US
NHS could pay up to 25% more for innovative drugs, but exports will be tariff free for three years
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OpinionWhat’s on your lab technology wish list?
Once-magical tools are now mundane. What will the next miracles be?
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ResearchRevived claims that antibiotics don’t kill bacteria with reactive oxygen prove controversial
Researchers say that multiple lines of evidence for hypothesis have now been undermined
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NewsCould Crispr cure HIV?
The first gene-editing therapies for HIV/Aids are entering trials but the virus is proving once again that it is a master at evading eradication
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OpinionA robotic helping hand
Mechanical labmates are making huge progress, but there are still big challenges to overcome
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ResearchAI-designed antibodies target antigens with atomic precision
Epitope-binding proteins designed from scratch by generative AI model
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ResearchAI cut development time of antibiotic that spares gut-friendly bacteria by two years
Animal tests show promise to target invasive strain of E. coli but approval for use in humans is still years away
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BusinessPfizer and Novo Nordisk’s battle over Metsera
Lawsuits fly in bidding war over developer of next generation weight loss drugs
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ResearchNanobodies from alpacas and llamas could hold the key to a universal antivenom
Novel nanobody mix protects against 17 African snake species