All Drug discovery and development articles
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SponsoredFacilitating the future
A view from the top at Johnson Matthey on the future of drug development
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Sponsored
AstraZeneca explores new frontiers through academic collaborations
The important of partnerships between industry and academia to drive innovation
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Business
New antiviral impresses against Covid-19
Merck & Co and Ridgeback’s molnupiravir reduces risk of hospitalisation and death, and may work against other coronaviruses
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Opinion
Where are the Covid-19 drugs?
Small molecules appear to be lagging behind development of vaccine and antibody treatments
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Research
Programmable peptoid template for disrupting protein–protein interactions inside cells
System optimises residues involved in binding target independently from those that promote membrane permeability
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Research
Method to make unusual oligonucleotides could be a boon for gene therapy drugs
Synthesis can insert unusual linkages into DNA molecules while rivalling industry standard chemistry in speed and efficiency
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Business
Fully synthetic proteins make tailored medicines
Bright Peak Therapeutics makes modified protein drugs from scratch
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News
Explainer: The science of alkyl nitrites aka poppers
From their origins as 19th century angina treatment to becoming an important part of gay subculture, these recreational drugs exist in a legal limbo
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Webinar
Automated capsule chemistry with Synple: do more, faster
Synple’s automated synthesis technology allows discovery chemists to accelerate research and improve efficiency
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Business
The multi-pronged search for Covid-19 treatments
Drugs that block infection or reduce inflammation will complement vaccine protection
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Business
Budget cuts at UK medicines regulator raise eyebrows
MHRA to cut 300 jobs amid financial pressures arising from Brexit
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Business
Brewing up plant-inspired medicines
Antheia reconstructs complex biochemical pathways in yeasts to speed up production of natural product-based drugs
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Business
Developing countries sidelined in Covid-19 vaccine scramble
Lack of funds and local manufacturing capacity has prevented Covax from competing with wealthier nations’ self-interest
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Business
Pfizer backs protein degrader drugs with Arvinas deal
$1bn investment to commercialise breast cancer treatment
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Webinar
Harness the power of electricity to make organic compounds
Join us to learn how to use batch-type cells in preparatory electrosynthesis
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Feature
One hundred years of insulin
Mike Sutton looks at the journey the diabetes treatment took from the Toronto miracle to mass-production – via a controversial trip to Stockholm
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Opinion
Opening up a cellular black box
Working out how biomolecular condensates work may reveal a lot about the success or failure of different drugs
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News
Race to understand Sars-CoV-2 variants amid fears virus might evade vaccines
Biochemical basis behind coronavirus variants’ success could hold key to defeating them
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Business
BMS and Eisai agree antibody-drug conjugate commercialisation deal
Companies will jointly develop cancer treatment, with BMS paying up to $3 billion for shared rights
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Feature
Supermetals versus superbugs
With pathogenic bacteria rapidly overcoming our arsenal of organic antibiotics, James Mitchell Crow asks if it is time to revisit metal-based antimicrobials
