All Drug discovery and development articles
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FeatureSeparating turmeric fact from fiction
Thousands of papers have been published on curcumin’s healing potential, but its usefulness is not yet proven, finds Andy Extance
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Webinar
AI and deep learning for chemistry with Pipeline Pilot
Join us on 20 November at 3pm (GMT) to learn how teams can effectively collaborate, manage and implement machine learning using Pipeline Pilot from Dassault Systèmes
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Opinion
Will computers ever discover drugs from scratch?
With enough understanding and computing power, it should be possible, but will it happen?
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Webinar
Advantages of characterising pharmaceuticals using DSC and TGA
Join us on 3rd December at 3pm to learn how APIs, excipients and formulations can be investigated by differential scanning calorimetry and thermogravimetric analysis
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Business
The rise of venture philanthropy
More and more charities are investing in companies, and looking for returns on that investment, as an alternative to traditional grants
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Research
Alzheimer’s therapy has click chemistry use, then remove, brain copper build-ups
In situ drug synthesis catalysed by endogenous copper
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Research
Metallohelices emulate antimicrobial peptides
Scientists move away from traditional drug candidates to evade resistance
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Business
Sixth in a line of Alzheimer’s drugs fails in trials
Treatments designed to stop amyloid peptide formation all seem to cause cognitive impairment rather than prevent it
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Sponsored
The importance of solid form science in modern drug development
A recent study suggests that around 40% of drugs with market approval exhibit poor water solubility and although this is not a new problem, solutions like those offered by Johnson Matthey are still relevant to today’s pharma market
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Research
Elusive protein and key to many tropical diseases found after decades of searching
Discovery offers powerful new target to treat trypanosome parasite illnesses that affect millions
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Opinion
Embracing structural disorder
Medicinal chemists need to overcome their fear of fuzzy proteins
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Research
Retrosynthetic algorithm broadened to design similar, but different, molecules
Chematica can now design efficient syntheses for large compound libraries
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Sponsored
Accurate temperature control achieving big results, on a small scale
Radleys’ compact reaction station brings accurate temperature control to chemical scientists managing small-scale experiments
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Opinion
Are new drugs better than existing ones?
Should companies be made to change the way they run clinical trials?
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Research
Modified metallohelices show medical potential
Post-assembly click reactions on helical metal complexes produces biological activity akin to that of the arrow poison ouabain
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Sponsored
Multidisciplinary science kick starts innovation
Nanoform scientists discuss how their diverse personalities and scientific backgrounds foster innovation, helping them tackle problems from different angles, and design better processes
