All Drug discovery and development articles
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BusinessWeight-loss drug shortages prompt copycats and counterfeits
Novo Nordisk and Eli Lilly have struggled to meet huge demand for new hormone mimic obesity treatments
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ResearchUnderwater device reveals marine chemical diversity
I-Smel device probes metabolites produced by Mediterranean sponges
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FeatureBattling long Covid with drugs
The challenge of finding drugs for a poorly understood disease with many symptoms is clear. Clare Sansom looks at the work going on to help the people suffering in its shadow
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FeatureThe drug developers fighting the antibiotic resistance problem
Andy Extance talks to the researchers innovating across different drug classes in the hunt to develop new treatments
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FeatureWho will pay for new antibiotics?
Governments around the world are starting to consider alternative funding models and incentives for antibiotics. Katrina Megget asks if it is enough
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ResearchA force against fungi
With antifungal resistance on the rise, Leah Cowen’s lab wants to identify molecules that can capitalise on vulnerabilities in fungal pathogens
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OpinionSurviving in the war of all against all
Cancers and bacteria develop resistance to drugs in remarkably similar ways
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FeatureCharting the rise in antimicrobial resistance
We look at the data behind antibiotic drug discovery and development, bacterial resistance and the financial problems with the current business model
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ResearchSynthetic peptide mimics can act as antivirals
Peptoids disrupt enveloped viruses’ lipid membranes as well as targeting fungi and bacteria
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ResearchRevived Neanderthal and Denisovan peptides show antibiotic activity
Molecular-scale ‘Jurassic Park’ process could uncover new medicines
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OpinionCould cheap CRO rates threaten to destabilise biotech?
Pharmaceutical pipelines are heavily dependent on contract research organisations; we can’t afford for them to fail
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ResearchClick chemistry offers new, efficient process to produce unique cancer-fighting antibodies
Chemical approach is fast and flexible and could be an alternative o using protein engineering
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BusinessRevolutionising RSV prevention
New vaccines and a long-acting antibody aim to protect older adults and babies from respiratory syncytial virus
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CareersWorking at the forefront of AI
Petrina Kamya’s curiosity has led her across sectors to become a leader in drug discovery
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BusinessThe diabetes drugs aiming to aid weight loss
Can peptide hormone mimics avoid the side effect pitfalls of previous weight loss treatments?
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BusinessUS supreme court confirms Amgen’s cholesterol antibody patents invalid
Decision could mean patent descriptions need to be even more detailed, and hence expensive
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WebinarBuilding organisational consensus around the tools of digital chemistry
Learn how change agents at Johnson Matthey developed a coalition of support for data-driven science
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BusinessMerck & Co to buy immunology specialist Prometheus
$10.8 billion cash deal give Merck rights to late-stage candidate for two inflammatory bowel conditions