Drug discovery and development
The latest chemistry news and research on drug discovery and development, including cancer drugs, antibiotics, vaccines and drug screening, from the Royal Society of Chemistry's magazine, Chemistry World
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ResearchNew class of antifungals show potent effects against priority pathogens
Coniotins, found in another fungus, is effective against drug-resistant pathogenic fungi
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WebinarLost in space, found in data: real-world scientific exploration and discovery
Join us on 14 October as we navigate the world of multidimensional spaces in data discovery methodology
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ResearchAntibiotics designed with the help of AI attack bacteria in entirely new ways
Two new compounds display potent activity against deadly drug-resistant bacteria
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BusinessWill oral weight loss drugs challenge injectables?
Pills may offer convenience for manufacturers, but it’s not clear they will overtake existing drugs
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BusinessThe challenge of developing oral alternatives to peptide weight loss drugs
Companies are racing to develop alternatives to injectable diabetes and weight loss drugs
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NewsUS government cancels mRNA vaccine research
Experts fear industrial and academic research may move abroad after infectious disease projects cancelled
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BusinessMerck & Co to cut 6000 jobs, Moderna to cut around 500
Both firms aiming to make significant reductions in annual costs by reorganising
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ResearchAI tools turned to creating designer proteins for personalised cancer therapies and antibiotics
Powerful new class of AI model could dramatically speed up process of producing new kinds of drug candidates
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NewsAs AI-designed drug looks to pass final hurdle, will this tech change drug discovery forever?
AI-led drug for chronic lung disease set to enter phase 3 clinical trials, though experts remain divided on AI’s impact in pharma
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OpinionChina’s drug development charge
Reforms and state support have fuelled domestic and foreign investment in pharmaceutical
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ResearchDNA barcodes can make drug discovery screens miss potential medicines
Flawed data is likely compromising machine learning methods
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BusinessUS approves twice yearly injection to prevent HIV
Yeztugo (lenacapavir) provided near-total protection against infection in clinical trials
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FeatureHibernation awakens interest for drug discovery
With many different species entering torpor for a variety of reasons, scientists are looking to their sleepy secrets for ways to treat human diseases. Anthony King reports
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ResearchAbundant alkanes become gaseous alkylating agent with flow chemistry
Photocatalytic process can carry out late-stage optimisation of drug candidates
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BusinessSanofi to buy Blueprint Medicines for over $9 billion
Blueprint has one approved drug and enhances Sanofi’s immunology portfolio
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OpinionIgnoring women’s health shouldn’t be an option
Developing therapies for conditions that predominantly affect women is a neglected, but enormous, opportunity
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WebinarModelling amorphous solid dispersion (ASD) release mechanisms
Learn how thermodynamic modelling and molecular simulation can help our understanding of amorphous solid dispersion
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FeatureManaging the menopause
The end of ovulation will affect almost all women, but current treatments could be improved. Rachel Brazil reports on the efforts to find a better solution
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OpinionWomen are not just another confounding factor in drug development
Ignoring physiological differences between the sexes is indefensible
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OpinionIn search of truth and rules
To codify and predict ever more complex phenomena is one of science’s great drivers