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All Drug discovery and development articles
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PodcastRemdesivir
Will new clinical trials for Covid-19 give remdesivir a second chance? Ben Valsler introduces the broad-spectrum antiviral that didn’t quite make it as the Ebola drug it was originally planned to be
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Research
Structural studies offer glimpse of how coronavirus initiates human cell invasion
Researchers studying virus receptor-binding domains suggest virus could have passed directly from bats to humans
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Business
Can existing drugs slow Covid-19?
The fastest route to treatments may be to repurpose existing drugs – if they work
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Podcast
Chloroquine and hydroxychloroquine
The Covid-19 pandemic – and some very high profile backing – has led to malaria drugs chloroquine and hydroxychloroquine hitting the headlines worldwide.
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Research
Potent coronavirus drug candidate designed using 3D structure of key viral enzyme
Inhibitor of Sars-CoV-2 protease shows promise in early animal tests
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News
UK researchers receive £20m to start coronavirus treatment research
Two vaccine trials among six projects that win funding
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Sponsored
Metathesis enables everyday innovation
For process chemists, simple solutions to complex problems are crucial. Metathesis is a cost-effective, reliable and scalable tool that enables innovation
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Sponsored
Marrying personalised medicine with the mainstream
By eliminating waste and confronting supply chain issues, the Medicines Manufacturing Innovation Centre is bringing personalised medicine to healthcare
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Research
Targeted nanoparticles swell-up to kill cancer cells
Nanoparticles covered with charged ligands can kill errant cancer cells but leave normal cells unharmed
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Podcast
Minoxidil and Finasteride
Catherine Hodges explores the chemical solutions to thinning hair and patchy beards, examining the popularity of minoxidil and the cautionary tale of finasteride
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Business
RNA vaccines are coronavirus frontrunners
Several groups have potential Sars-CoV-2 vaccines ready or close to testing, thanks to rapid development pathways
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Research
Metal complexes outperform organics in antimicrobial analysis on crowdsourced compounds
Could this study prompt drug developers to rethink their reluctance to making metal-based pharmaceuticals?
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Research
AI tool screens 107 million molecules, discovers potent new antibiotics
Deep learning approach could help in fight against drug-resistant bacteria
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Opinion
Two heads are better than one
Bifunctionals show that sometimes simply tethering two useful molecules together unlocks some useful activity
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Feature
Adjuvants: vaccines’ hidden helpers
Anthony King examines a crucial part of vaccines that can significantly boost their performance, but which often go unrecognised
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Business
The race to fight coronavirus
While genome sequences enable testing and vaccine efforts, companies are donating existing antiviral drugs to explore repurposing
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Sponsored
Transforming innovation for startups
Green polymer specialists Novomer and biotech startup SynbiCite optimised industrial and biotech processes using design of experiment software from JMP
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Feature
The search for cancer vaccines
Claire Jarvis looks at ongoing work to prevent the disease – and convince a sceptical community of their seriousness
