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ResearchFirst natural Diels–Alder enzyme discovered in mulberry tree
Enzyme beats most synthetic catalysts when it comes to enantioselective intermolecular [4+2] cycloadditions
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Research
Decoding the chemistry behind cicada’s bacteria-killing wings
Organisation and composition of nanostructures help to explain unique properties
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Podcast
DMT – Dimethyltryptamine
Georgia Mills investigates the psychoactive found in ayahuasca that may mirror near-death experiences
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Research
Unnatural cyclic amino acids push limits of ribosome
Expanding repertoire of monomers for ribosome-mediated polymerisation is boon for scientists wanting to harness nature’s protein factories
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Podcast
Chlorine dioxide
Katrina Krämer investigates how industrial-strength bleach became promoted as ‘miracle mineral supplement’ – a supposed ‘cure’ for autism, cancer and even Covid-19.
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Research
Photosynthesis rewired to generate hydrogen
Gene transplant repositions algal hydrogenase so that it directly captures electrons from photosystem I
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Research
Yeast thriving in hydrogen hints at possibility of life on exoplanets
First demonstration of non-adapted microorganisms growing in 100% H2 shows that life could exist even under seemingly hostile conditions
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Research
Trapped enzyme reveals its unexpected shape-shifting ability
Metamorphic protein confined in nanopore found to switch between different 3D shapes as it catalyses a redox reaction
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News
Explainer: how do disinfectants tackle Covid-19?
What we know about the biocides that attack the virus, and how you should use them
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News
Science steps up a gear as struggle to both understand and fight coronavirus intensifies
Research that might have taken years is being turned around in months as journals fast-track Covid-19 manuscripts
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Research
Structural studies offer glimpse of how coronavirus initiates human cell invasion
Researchers studying virus receptor-binding domains suggest virus could have passed directly from bats to humans
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Research
DNA instructions pack proteins into unique crystal structures
Process could aid discovery of materials that exploit specific protein functions, such as drug molecules or biocatalysts
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Research
Potent coronavirus drug candidate designed using 3D structure of key viral enzyme
Inhibitor of Sars-CoV-2 protease shows promise in early animal tests
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Feature
Uncovering how the spliceosome makes the cut
Clare Sansom looks at the complex world of the spliceosome, a molecular machine in all our cells
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Research
Cheating bacterium becomes antibiotic-tolerant at expense of other species
Coexistence triggers counterintuitive antibiotics response in bacteria, which could be used to tackle hardy species
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Research
Fossilised bones inspire long-term DNA data storage
Earth alkali salts found to stabilise synthetic DNA
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Research
Unlocking geological time capsules with analytical chemistry
Blavatnik award winner Kirsty Penkman discusses her research developing techniques to date fossils
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Research
Snakes swap toxic toads for fireflies but retain unique chemical defence
Defensive toxins reveal evolutionary shift in snakes’ diet
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Research
Detailed 3D coronavirus spike map offers hope for vaccine development
Structure determined at ‘remarkable’ speed in little over a month
