An overlooked bonding motif appears in many more proteins than was previously realised
By 
Anthony King2025-06-11T08:30:00
Covalent nitrogen–oxygen–sulfur linkages could be a new target for potential drugs
A systematic survey of archived protein structures has revealed dozens of examples of a previously overlooked covalent bonding motif. Mapping these nitrogen–oxygen–sulfur (NOS) linkages could open the door to new therapies and better engineering of proteins.