Bradley van Paridon
ResearchProtein design takes big leap forward as model produces enzymes almost as effective as nature’s
New iteration of RoseTTAFold Diffusion optimises side chain placing to break bonds
NewsProposal takes aim at risk posed by ‘chemical cocktails’
Mixture allocation factor would weigh toxicity of chemicals as a whole
ResearchAI-designed antibodies target antigens with atomic precision
Epitope-binding proteins designed from scratch by generative AI model
ResearchSeventy-year search for simpler route to valuable reactive intermediate ends
Ortho-quinodimethane made under mild conditions from common reagents
NewsChemists urged to build a greener future by Stockholm declaration document
‘Father of green chemistry’ Paul Anastas among those spearheading call to action
ResearchHybrid metabolism allows bacterium to get most out of fermentation and respiration
Engineered E. coli can turn unusable carbon sources into chemical feedstocks
ResearchE. coli engineered to become methanol addict to make industry feedstocks
Bacterium could head off food versus fuel dilemma by producing chemicals from agricultural waste
ResearchUnravelling enzyme pathway of Taxol precursor brings synthetic production of cancer medicine closer
Expression of nine genes in tobacco plants led to formation of complex precursor of drug
ResearchInvasive zebra mussels’ unique sticky threads unraveled
New understanding of byssal threads finds similarities with spider silk making them unlike any other mussels’
ResearchSustainable glue made from soy oil and tannin outperforms best commercial adhesives
Mussel inspired plant-based adhesive still requires optimisation but shows promise
ResearchLife’s energy currency ATP made using electricity from the grid for the first time
Simplified system uses just four enzymes with socket-supplied electrons replacing biochemical energy
NewsExplainer: what is green chemistry and why does it matter?
25 years after the field’s 12 principles were first laid down, green chemistry has moved into the mainstream
News‘Will we have the will to invest, the will to change?’: green chemistry 25 years on
Father of green chemistry says we’ve shown we can change, but can we transform the chemical sciences?
ResearchOyster mushroom unleashes chemical warfare on its nematode prey
Fungus discovered to be using 3-octanone to paralyse and kill worms
CareersDocumenting hazards in the lab for pregnant chemists
After failing to find the safety information they needed, two pregnant chemists began a project to review hazards in labs
ResearchCoca plants’ production pathway for cocaine finally unravelled
167-year-old biosynthetic mystery may be solved
ResearchTeixobactin’s two pronged antibiotic attack mechanism revealed
Understanding of formation of deadly supramolecular structures could help build improved antimicrobials
ResearchMOF nurtures stem cells to differentiate into neuronal cells
Challenging task of coaxing stem-cells to differentiate could become easier thanks to metal-organic frameworks
ResearchBiochemical mystery unfolds as elemental metals found in Alzheimer’s patients’ brains
In a discovery that raises more question than it answers, researchers have found zero-oxidation-state iron and copper deposits inside amyloid plaques
NewsChemistry at work in e-liquids is still poorly understood, worrying researchers
New compounds with potentially harmful effects on the lungs can form from the mixture of flavours and solvents – even at room temperature