Medicine Nobel prize recognises discovery of protective ‘security guard’ regulatory T cells

2025 Medicine Nobel Prize winners

Source: © Niklas Elmehed/Nobel Prize Outreach

Research explained how body protects itself from the immune system, offering new ways to treat autoimmune disease

The 2025 Nobel prize in physiology or medicine has been awarded jointly to three scientists – two based in the US and one based in Japan – for their discoveries regarding the role of regulatory T cells in keeping the immune system in check. Faulty regulatory T cells can result in autoimmune disease and as a result there has been considerable interest in this system from drugmakers.