All Reactions and synthesis articles
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BusinessAn evolution in pharma outsourcing
Contract services firms are becoming increasingly sophisticated and embedded in the ecosystem of drug development
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Opinion
Are elemental analysis guidelines appropriate?
The standard journal requirement of ±0.4% for carbon, hydrogen and nitrogen is not statistically sound
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Research
Exclusive polymers made using mechanochemistry
Ball-milling method avoids solubility issues with ring-opening metathesis polymerisations
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Research
Mineralisation makes chemical recycling of fluoropolymers a possibility
By using molten sodium hydroxide, researchers show they can produce fluorite from fluoropolymers in a two-step process
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Research
Cobalt nanoparticles behind alternative to lead-based Lindlar catalyst
Dietary supplements market could benefit from catalyst that performs the semi-hydrogenation of a range of vitamin precursors
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Webinar
How to profit from recent innovations in small molecule drug discovery
Reduce risk, cost and wasted time in the new era of small molecule drug discovery
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Research
First synthesis of aza-triangulene in solution
Chemists synthesised and isolated unstable species and its cation in crystalline form
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Research
Double heptagon-containing fullerenes produced by low pressure combustion
Study finds identical nonclassical fullerene cores can created by separate processes
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Research
Multitasking boron catalyses first aldol reaction from esters
Using esters instead of aldehydes offers chemists a completely new retrosynthetic disconnection
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Research
Chemical decapitation renders PFAS harmless
An unexpected mechanism destroys persistent perfluorinated chemicals, though the method isn’t ready for the field yet
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Research
Artificially evolved enzyme tackles tricky cross coupling
Directed evolution on the metalloenzyme cytochrome P450 creates a catalyst for making macrocyclic antibiotics
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Research
Perfluorocubane catches electron in molecular box
Cube-shaped molecule can hold a single electron – a real-life version of the ‘particle in a box’ principle from quantum mechanics textbooks
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Research
Electrons become chiral reagent in polymer synthesis
Chiral polymer made from completely achiral chemicals using only electrons’ angular momentum
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Business
Rocket-powered carbon dioxide conversion
Barton Blakeley is lowering the carbon footprint of silica and other materials
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Webinar
Empower your drug design & synthesis with vibrational circular dichroism (VCD)
Discover the advantage and benefits of VCD compared to other analytical techniques and learn how to develop a more efficient workflow
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Research
Nature inspires greener generation of metal hydrides to make formic acid from CO2
The iron–sulfur cluster catalyses the electrocatalytic formation of manganese hydrides
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Webinar
Using calorimetry during battery operation to solve development challenges
Join us as we assess safety, energy density and longevity of battery cells through high-resolution isothermal calorimetry
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Research
Clever carbene synthesis replaces notoriously hazardous chemistry
Reactive carbon compounds can now be made from aldehydes instead of explosive or unstable reagents
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Research
Time-resolved spectroscopy shines new light on migratory insertion mechanism
Using lasers to probe metal-centred reactions leads to new understanding of highly reactive catalytic intermediates
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Research
Electrochemical ‘game-changer’ could make aniline production greener
Sustainable production of important feedstock for dyes, drugs and herbicides is scalable
