All Reactions and synthesis articles
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ResearchCarbon fibre plasma reactor enables extreme synthesis without compromise
Reactor can reach temperatures of 8000K without the need to choose between high temperatures or stability
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ResearchRobotic chemistry lab joins forces with Google AI to predict then make new inorganic materials
Algorithm discovered more than 2 million inorganic structures
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ResearchNew silicon-based protecting group removable with blue light
Benzoyldiisopropylchlorosilane protects primary, secondary and tertiary alcohols, and also works alongside other protecting groups
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NewsFuture House wants to build an AI biologist. They’re looking to a chemistry LLM for inspiration
ChemCrow has already recorded success researching, designing and producing an insecticide on its own
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ResearchSkeletal editing that simply swaps aromatic carbons for nitrogens will aid drug discovery
Atom-swapping chemistry gains two new techniques that are ready to use
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ResearchPlasma–microdroplet fusion enables catalyst-free amine alkylations
Microdroplet chemistry improves selectivity of plasma-mediated alkylation reactions
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OpinionSlow march of the retrosynthesis robots
Software synthesis suggestions are hampered by biased and incomplete datasets
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ResearchActivating a chemical reaction by ‘flipping a switch’
A low-cost microfluidic reactor could cut the environmental footprint of synthesis by directing electrons via an external electric field
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ResearchCarbon’s anti-aromatic allotrope is ringing the changes
The first synthesis of an anti-aromatic ring of pure carbon using atom manipulation
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ResearchUnexpected oscillations clarify mechanism of 100 year-old Fischer–Tropsch reaction
Discovery could pave the way to improved design of catalysts
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ResearchPlaying her part in building South Africa’s scientific reputation
Meet Pinkie Ntola, an early-career Black researcher who is passionate about being a credible scientist, an inspiring teacher and a supportive mentor
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ResearchSimple substitution creates subset of rhodamine fluorophores with extreme solubility
Tetramethyl-substituted 3-phosphonorhodamines look set to find use in cellular imaging
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ResearchLong-lived excited states open the door to earth-abundant metal photocatalysts
New findings show that cobalt (III) complexes can catalyse reactions not previously thought possible
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ResearchElectrophilic aromatic bromination study casts doubt on textbook intermediate
New computational evidence that electrophilic aromatic bromination actually occurs via an addition–elimination mechanism
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FeatureThe quantum dot story
Julia Robinson explains how quantum dots went from a theoretical prediction to everyday reality and earned Alexei Ekimov, Louis Brus and Moungi Bawendi the 2023 Nobel prize in chemistry
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ResearchLasers and lithium team up for ammonia production at ambient conditions
A pioneering method uses lasers and lithium salts to fix nitrogen with record-breaking yields
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WebinarBattery material changes in real-time: silicon anode structural evaluation via isothermal microcalorimetry
Join us on 9 November to learn about battery material changes and how to accelerate battery development using cutting-edge in-operando isothermal microcalorimetry
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ResearchMOFs offer safer solution for handling fluorinated gases that can ‘tame the tiger’
Compounds vital in medicinal chemistry and imaging can be stored ready to use at room temperature
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ResearchDoubly oxidised carbene tests the limits of the octet rule
Removal of two non-bonding electrons creates four-electron intermediate that could find use in synthesis