All Reactions and synthesis articles
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ResearchChiral chemical fuels trigger two very different supramolecular self-assemblies
Handedness of self-assembling peptides might explain the origins of homochirality in biological systems
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Research‘Microlightning’ released by peeling tape can drive chemical reactions
Intense localised electric fields can break bonds
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ResearchStudy challenges notion that solution-phase organic reactions are unfeasible at high temperatures
Capillary synthesis at 500°C converts N-substituted pyrazoles into their isomers within five minutes
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ResearchUnusual radical reaction powered by strained substrates
Single-electron strain-release produces pharmaceutical building blocks
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ResearchSuper-fast automated synthesis promises to make chemistry accessible to many more
Order of magnitude improvement in speed result of technology optimisation
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ResearchElectrochemical acid–base reactions can be fine tuned to control reactivity
Two new parameters can offer tunability to a wide range of electrochemical reactions
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ResearchMolecular crystal motors completely powered by light
Chemists in Saudi Arabia and the US have created tiny machines made from crystallised molecules that continuously move when exposed to light
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ResearchBoron cluster family breaks electron counting rules
Rare structures have unusual deltahedral shapes
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ResearchMachine learning could ‘change the paradigm’ for polaritonic chemistry
Model reveals influence of vibrational strong coupling during light-driven reaction
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ResearchIron salts catalyse the creation of carbenes for cyclopropanation
A new strategy to synthesise non-stabilised carbenes gives access to cyclopropanes with potential in drug discovery
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ResearchUnusual bridging fluorine discovered in one-of-a-kind interhalogen ion
Similarity to MgAgAs crystal structure takes researchers by surprise
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ResearchRegioselective nitrogen-insertion reaction is latest addition to skeletal editing toolbox
Protocol transforms arenols into benzazepines
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ResearchRiding the microwave: three chemists share their stories
Disagreements surrounding non-thermal effects didn’t stop microwave reactors becoming a standard part of laboratory life
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ResearchSteroid separation made easy with photoswitchable coordination cage
Light-activated coordination cage purifies progesterone
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ResearchE. coli rewired to shift carbon flow towards C4 chemicals
Bioengineering strategy creates evolutionary advantage linking cell growth with product formation
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ResearchIon-beam experiments probe fundamentals of hydronium–hydroxide neutralisation
Researchers uncover new insights into one of chemistry’s most fundamental equilibrium reactions
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FeatureEditing polymer backbones
Changing the chemical makeup of a polymer backbone could revolutionise how we make, use and even recycle plastics. James Mitchell Crow reports
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ResearchPhotochemistry converts dry-cleaning solvent waste into useful chemicals
One-pot reaction offers way to upcycle industrial solvent waste