All Reactions and synthesis articles
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Research’Photoredox catalysis goes asymmetric’: counterion strategy a breakthrough in reaction control
Ion-pairing enables chemists to reach previously inaccessible enantiomers
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Research
AI model accurately classifies reaction mechanisms
Machine learning ‘surpasses chemist experts’ in identifying chemical processes
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Sizing of temperature control units for reactor applications
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Research
3D-printed single-atom catalysts brings industry use closer
Printing technique could allow more widespread application of exceptional catalytic particles
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Research
Streamlined synthesis of quinine showcases sustainable organic strategy
Five pot synthesis delivers highest yield of antimalarial to date
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Research
Photochemistry frees arene functionalisation from metals
Sulfonium salts offer new possibilities for the alkylation and cyanation of aromatic molecules
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Research
Mechanochemistry set to expand availability of organomanganese reagents
Ball milling method avoids problems surrounding solution-based chemistry when synthesising arylmanganese nucleophiles
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Research
Benchtop machine automates synthesis of drug screening hits
System could boost the efficiencies of drug discovery campaigns
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Research
Manganese complex behind method for preparing silanols that uses water as an oxidant
By using water as an oxidising agent, the reaction eliminates additional reagents and unwanted side-products
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Sponsored
Application of chiller technology to laboratory distillations
Download this white paper to discover how accurate and reproducible temperature control impacts solvent recovery, and can lead to improved health and safety, a lower risk of environmental contamination and even a cheaper water bill
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Feature
The diamond synthesisers
Nina Notman takes a whistle-stop tour of the synthetic diamond industry and learns about some of the applications its lab-grown diamonds are being used for
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Sponsored
Catalysing change: innovative solutions for greener chemistries
New ligands are enabling the enormous potential of cross coupling reactions to solve challenges in a range of industries
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Sponsored
Driving the transition to sustainable air travel
Drop-in replacements for aviation fuels are an essential part of decarbonising the industry
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Research
Coca plants’ production pathway for cocaine finally unravelled
167-year-old biosynthetic mystery may be solved
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Opinion
Embracing oddities
When new chemistry looks like alchemy or witchcraft, it’s worth taking notice
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Research
Mystery surrounding metalation reaction’s reagent excess solved
Multiple ‘base-eating’ aggregates discovered in classic directed ortho lithiation
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Research
Gigantic database of building blocks will help artificial intelligence uncover new organocatalysts
Publicly available dataset containing thousands of structures could help chemists develop data-driven reaction optimisation methods for organic synthesis
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Research
Homogeneous catalysis boosted by electrochemical recovery of precious metal complexes
Process can recover metals from industrially important catalysts
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Research
Fully automated synthesis robot sets new record in stereospecific carbon–carbon bond formation
The robotic platform can make six carbon–carbon bonds without human guidance
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