All Reactions and synthesis articles – Page 2
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Research
Explainer: What are water microdroplets and why are chemists talking about them?
Researchers are struggling to agree on the underlying reasons for accelerated rates and altered reaction mechanisms in water microdroplets. Here’s what we do know and where open questions lie…
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Research
Water microdroplet chemistry is contentious, here’s why
Are water microdroplets chemical dynamos or are their apparent effects experimental artefacts? Rebecca Trager investigates
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Research
First GPT-4-powered AI lab assistant independently directs key organic reactions
Large language model takes control after being prompted to do Suzuki and Sonogashira couplings
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Research
Computer vision accelerates self-driving reaction workups from being automated to autonomous
Platform understands significance of solid residues, liquid levels, homogeneity, turbidity and colours
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Opinion
Exploring new fragments of chemical space
How medicinal and process chemists are working together to build better drugs
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Research
Fast flow-chemistry set-up facilitates sulfur-fluoride click chemistry
A modular method makes the most of flow-chemistry to create click-ready reagents selectively and efficiently
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Article
Chemistry needs the human element - here’s why
Automated R&D has huge potential, but we need to be kept in the loop
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Feature
Cubanes help drugs take the strain
Medicinal chemists are increasingly exploring strained ring systems, George Barsted reports, believing they can serve as replacements for conventional building blocks in pharmaceuticals
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Research
Carbon fibre plasma reactor enables extreme synthesis without compromise
Reactor can reach temperatures of 8000K without the need to choose between high temperatures or stability
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Research
Robotic chemistry lab joins forces with Google AI to predict then make new inorganic materials
Algorithm discovered more than 2 million inorganic structures
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Research
New silicon-based protecting group removable with blue light
Benzoyldiisopropylchlorosilane protects primary, secondary and tertiary alcohols, and also works alongside other protecting groups
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News
Future House wants to build an AI biologist. They’re looking to a chemistry LLM for inspiration
ChemCrow has already recorded success researching, designing and producing an insecticide on its own
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Research
Skeletal editing that simply swaps aromatic carbons for nitrogens will aid drug discovery
Atom-swapping chemistry gains two new techniques that are ready to use
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Research
Plasma–microdroplet fusion enables catalyst-free amine alkylations
Microdroplet chemistry improves selectivity of plasma-mediated alkylation reactions
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Opinion
Slow march of the retrosynthesis robots
Software synthesis suggestions are hampered by biased and incomplete datasets
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Research
Activating a chemical reaction by ‘flipping a switch’
A low-cost microfluidic reactor could cut the environmental footprint of synthesis by directing electrons via an external electric field
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Research
Carbon’s anti-aromatic allotrope is ringing the changes
The first synthesis of an anti-aromatic ring of pure carbon using atom manipulation
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Research
Unexpected oscillations clarify mechanism of 100 year-old Fischer–Tropsch reaction
Discovery could pave the way to improved design of catalysts
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Research
Playing her part in building South Africa’s scientific reputation
Meet Pinkie Ntola, an early-career Black researcher who is passionate about being a credible scientist, an inspiring teacher and a supportive mentor