All Reactions and synthesis articles – Page 2
-
ResearchNew analysis raises doubts over autonomous lab’s materials ‘discoveries’
Experimental and computational issues flagged as researchers conclude that a fully automated lab failed to make new materials
-
ResearchExplainer: What are water microdroplets and why are chemists talking about them?
Researchers are struggling to agree on the underlying reasons for accelerated rates and altered reaction mechanisms in water microdroplets. Here’s what we do know and where open questions lie…
-
ResearchWater microdroplet chemistry is contentious, here’s why
Are water microdroplets chemical dynamos or are their apparent effects experimental artefacts? Rebecca Trager investigates
-
ResearchFirst GPT-4-powered AI lab assistant independently directs key organic reactions
Large language model takes control after being prompted to do Suzuki and Sonogashira couplings
-
ResearchComputer vision accelerates self-driving reaction workups from being automated to autonomous
Platform understands significance of solid residues, liquid levels, homogeneity, turbidity and colours
-
OpinionExploring new fragments of chemical space
How medicinal and process chemists are working together to build better drugs
-
ResearchFast flow-chemistry set-up facilitates sulfur-fluoride click chemistry
A modular method makes the most of flow-chemistry to create click-ready reagents selectively and efficiently
-
ArticleChemistry needs the human element - here’s why
Automated R&D has huge potential, but we need to be kept in the loop
-
FeatureCubanes help drugs take the strain
Medicinal chemists are increasingly exploring strained ring systems, George Barsted reports, believing they can serve as replacements for conventional building blocks in pharmaceuticals
-
ResearchCarbon fibre plasma reactor enables extreme synthesis without compromise
Reactor can reach temperatures of 8000K without the need to choose between high temperatures or stability
-
ResearchRobotic chemistry lab joins forces with Google AI to predict then make new inorganic materials
Algorithm discovered more than 2 million inorganic structures
-
ResearchNew silicon-based protecting group removable with blue light
Benzoyldiisopropylchlorosilane protects primary, secondary and tertiary alcohols, and also works alongside other protecting groups
-
NewsFuture House wants to build an AI biologist. They’re looking to a chemistry LLM for inspiration
ChemCrow has already recorded success researching, designing and producing an insecticide on its own
-
ResearchSkeletal editing that simply swaps aromatic carbons for nitrogens will aid drug discovery
Atom-swapping chemistry gains two new techniques that are ready to use
-
ResearchPlasma–microdroplet fusion enables catalyst-free amine alkylations
Microdroplet chemistry improves selectivity of plasma-mediated alkylation reactions
-
OpinionSlow march of the retrosynthesis robots
Software synthesis suggestions are hampered by biased and incomplete datasets
-
-
ResearchActivating a chemical reaction by ‘flipping a switch’
A low-cost microfluidic reactor could cut the environmental footprint of synthesis by directing electrons via an external electric field
-
ResearchCarbon’s anti-aromatic allotrope is ringing the changes
The first synthesis of an anti-aromatic ring of pure carbon using atom manipulation
-
ResearchUnexpected oscillations clarify mechanism of 100 year-old Fischer–Tropsch reaction
Discovery could pave the way to improved design of catalysts