All enzymes articles
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ResearchChemical industry hasn’t yet developed an appetite for biocatalysis, survey finds
Misconceptions along with a lack of time and resources driving industry’s reluctant attitude to biocatalysis and chemoenzymatic catalysis
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BusinessRecycling plastic with enzymes
Carbios can return even hard-to-recycle polyester fibres and textiles to their constituent monomers
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FeatureFixing nitrogen fixing
Green ammonia promises a more sustainable future. Jamie Durrani talks to the researchers aiming to revolutionise the production of crucial fertiliser
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ResearchNMR reveals sialic acid biosynthesis in real time
Using NMR, scientists can directly measure sialic acid enzyme conversion velocities for the first time
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ResearchUnexpected autocatalytic effect gives light-driven enzyme a boost to synthesise green fuels
Discovery could enhance production of liquid fuels by algae
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ResearchDiverse pharmaceutical building blocks prepared with evolved enzymes
Computation guides enzyme evolution to produce high-value drug compounds
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ResearchNMR spectroscopy used to guide evolution of better enzymes
Identifying mutagenic ‘hotspots’ could speed development of new proteins
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ResearchDesigner catalyst with enzyme-like cavity splits water almost as fast as plants
Catalytic cleft offers new strategy to speed up hydrogen synthesis
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ResearchArtificially evolved enzyme tackles tricky cross coupling
Directed evolution on the metalloenzyme cytochrome P450 creates a catalyst for making macrocyclic antibiotics
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ResearchNature inspires greener generation of metal hydrides to make formic acid from CO2
The iron–sulfur cluster catalyses the electrocatalytic formation of manganese hydrides
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ResearchTheories on origin of enzymes’ catalytic power united
Transition state stabilisation and ground state destabilisation both reduce the energy barrier by enhancing charge density but vary in their timing
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ResearchMicrodroplets tackle scale-up issues for enzyme-photocoupled catalysis
Gas-spray reactor enhances light illumination efficiency and boosts rate of reaction
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ResearchAI-engineered enzyme eats entire plastic containers
Enzyme with only five amino acid alterations depolymerises 51 different PET products faster and at lower temperature than other proteins
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ResearchYeast engineered to convert methanol into heparin
Production levels are currently low, but researchers hope the method could one day mean pharma doesn’t have to rely on animals for this essential medicine
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ResearchIBM teaches reaction planning system to ‘speak enzyme’
RXN seeks to use enzyme catalysis to make chemistry more sustainable and resource efficient
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ResearchElectric field of ATP synthase suggests enzyme has functions beyond catalysis
Study links energy-making enzyme with proton migration in ATP formation, and reinforces predictions that its catalytic efficiency is around 90%
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ResearchEngineered enzyme speeds up sedate organic reaction
Biochemical optimisation applied to the Morita–Hillman–Baylis reaction
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ResearchEvolved enzymes carry out new-to-nature radical chemistry
Directed evolution produces enzymes that can ‘tame’ radical intermediates for asymmetric catalytic reactions
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FeatureThe labs pointing to a greener future for Africa
Tackling climate is not just a job for scientists in more developed countries. Munyaradzi Makoni talks to researchers in Kenya and South Africa to find out more
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ResearchGiant molecular cage protects plastic-eating enzyme
Caged protein withstands temperatures much hotter than its usual melting point and becomes 1000 times more resistant to solvents