All enzymes articles
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ResearchGiant molecular cage protects plastic-eating enzyme
Caged protein withstands temperatures much hotter than its usual melting point and becomes 1000 times more resistant to solvents
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Research
Mirror image enzyme constructs longest ever mirror DNA strand
Since chirally inverted DNA is more stable than its natural counterpart, it can be used to encode secret messages
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News
Machine learning delivers ‘human genome’ moment for proteins
Protein structure prediction tools AlphaFold and RoseTTAFold take the latest steps towards maturity and make their software open source
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Research
Molecular light switch speeds up tricky cyclodextrin synthesis
Reaction could lower cost of useful macrocycle
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Business
Engineering microbes to degrade contaminants
Allonnia is using synthetic biology to tackle major environmental challenges like PFASs, metals and plastic waste
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Research
Sortase A strategy could see ribosomal products reach further across chemical space
Compound libraries set to benefit from process that harnesses promiscuity of post-translation enzymes
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Research
Artificial enzyme sets record as it outperforms horseradish counterpart by factor of 12
Engineered nanoparticle achieves highest efficiency of any artificial enzyme when compared with natural peroxidase
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Research
The hole story of how cage molecules could transform synthesis and separation
Chemists are getting to grips with how to put molecules inside other molecules and how this could protect highly reactive reagents and create enzyme-like catalysts
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Research
New titration reagent helps identify the best amylase for the job
Fluorogenic compound plugs gap in industrial enzyme screening toolbox
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Feature
Unnatural selection in chemical systems
Great strides have been made in the lab with chemical systems that ape life’s behaviour
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Feature
Artificial enzymes: catalysis by design
Enzymes are nature’s ultimate catalysts and chemists are now on the verge of making their own versions from scratch
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Feature
Homogeneous C–H activation
In the final instalment of our grails series we look at how picking and choosing which bond to target holds the promise of transforming organic molecules at will
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Research
NMR findings suggest solution to enhanced diffusion dispute
Energy release rate may solve the puzzle of why the phenomenon is seen in some systems but not others
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Opinion
Making light of bioluminescence
Glowing may be a side-effect of a very different original purpose
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Research
Unnatural reaction benefits from computational tool that teaches an old enzyme new tricks
Method could generate artificial enzymes that are more suitable for directed evolution
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Research
First natural Diels–Alder enzyme discovered in mulberry tree
Enzyme beats most synthetic catalysts when it comes to enantioselective intermolecular [4+2] cycloadditions
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Research
Photosynthesis rewired to generate hydrogen
Gene transplant repositions algal hydrogenase so that it directly captures electrons from photosystem I
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Research
Trapped enzyme reveals its unexpected shape-shifting ability
Metamorphic protein confined in nanopore found to switch between different 3D shapes as it catalyses a redox reaction
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Research
Enzymes encapsulated in a golden cage perform in extreme conditions
No room for the proteins to denature but reactants can still get through
