All Life articles – Page 46
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OpinionWhat are the rate-limiting steps in drug discovery?
Getting more drugs to market is not just a chemistry problem
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ResearchCrowdsourced drug discovery pits half-forgotten compounds against neglected diseases
45 research groups donate 350 compounds to the first crowdsourced screening library
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FeatureReady for a Raman shift
Raman spectroscopy has been seen as a tool for physicists and chemists but Hayley Bennett finds it has the potential to cause a major shift in the way we do medicine
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ResearchLightning-inspired method makes ammonia with no catalyst
Plasma-enabled electrolysis produces the vital gas in high purity – but also consumes much more energy than current methods
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ResearchSelf-illuminating nanoparticles shine a light on cancer
Tumours trigger luminescence for imaging, then production of singlet oxygen to kill cancer cells
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ResearchEnzyme evolved that can perform reactions new to nature
New possibilities for organic synthesis with enzymatic C–H functionalisation
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ResearchSynthetic molecules fold up into abiotic proteins
Compound that self-assembles into giant folded ring could help scientists design bespoke abiotic proteins
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ResearchBlood pressure drug reacts with membrane lipids
Lipidation products add to evidence that biological membranes are far from chemically inert
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OpinionChiral curiosities
The challenges posed by asymmetry go hand in hand with fascinating insights into developmental biology
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ResearchNanodecoys lure and trap Zika virus
Gelatin nanoparticles camouflaged by mosquito membrane mop up virus and stop it crossing placenta
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ResearchDNA sugar could form on icy asteroids and comets
Water–methanol ices bombarded with UV simulate conditions found on comets and asteroids
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ResearchPore-forming toxins detect long strands of DNA
Lithium electrolyte helps aerolysin overcome electrostatic obstacle to detect ssDNA longer than 100 nucleotides
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ReviewGene Machine: The Race to Decipher the Secrets of the Ribosome
Venki Ramakrishnan tells the story of his journey from physics student to chemistry Nobel laureate
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PodcastGene Machine by Venkatraman ‘Venki’ Ramakrishnan – Book club
2009 Nobel prize winner Venki Ramakrishnan takes us on a personal and professional journey to uncover the secrets of the ribosome
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BusinessGSK and Pfizer joint venture creates new consumer healthcare giant
Enlarged GSK consumer health will have largest market share of any firm and be a leader in key countries
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ResearchLiquid analysis simultaneously checks for 71 elements
Technique delivers elemental fingerprint of everything from water to wine in minutes
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OpinionGene-editing put in the spotlight
What now after a rogue geneticist has created the first genetically modified humans?
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ReviewThe Book of Humans: The Story of How We Became Us
Adam Rutherford sets out to explain what it is that sets us apart from other animals
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