Medicinal chemistry – Page 61
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FeatureTransparency measures forced on pharma
Previous misdemeanours are compelling the pharmaceutical industry to be more open with financial information and clinical data, writes Nuala Moran
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ResearchMirror peptides hitch a lift into the cell
Hijacking nature’s tricks to smuggle drugs across the cell membrane
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ResearchNanoparticle studies leave the lab
Scientists take to the outdoors to show that single walled carbon nanotubes accumulate and persist in aquatic sediments
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FeaturePepping up antibiotics
Industry and academia are turning to antimicrobial peptides to find new antibiotics, Andy Extance discovers
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News
NIH wants scientists to consider sex in research
Preclinical and clinical research is overreliant on male test subjects which can cloud future work in humans
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Business
Review says cheaper drug is safe for eye disease
Cochrane collaboration says side effects of expensive Lucentis and off-label Avastin are similar
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FeatureFaster, cheaper, better diagnostics
Microfluidics researchers are aiming to bring new diagnostic devices into mainstream medicine. Mark Peplow reports
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FeatureChemistry in bloom
Sarah Houlton discovers the chemistry among the specimens at many botanical gardens
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ResearchPainkiller found in plants may not be natural after all
Cow pats from cattle fed tramadol could explain how the drug came to be in an African herb
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ResearchCoated nanoparticles show Alzheimer's promise
Gold nanoparticles functionalised with amino acid polymer inhibit the growth of amyloid fibres associated with neurodegenerative disease
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ResearchAntimalarial flow synthesis closer to commercialisation
Scientists in Germany hope their continuous flow method will boost accessibility of artemisinin-derived medicines
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ResearchHigher levels of some metals in e-cigarette smoke
Scientists call for regulators to help clear smoke and mirrors surrounding vaping safety
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ResearchCPU heat powers PCR disease detection
Computer and mobile phone combo detects Chagas disease in blood and could drive down diagnosis costs
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ResearchBringing chemical synthesis to the masses
Researchers hope simple system to build thousands of peptides without enzymes, cells or reagents will be accessible to all
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ResearchUrine test could catch lung cancer early
Cancer diagnosis could be accelerated using an approach that is low cost, rapid and non-invasive
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Business
Servier to appear in adverts over lack of transparency
Adverts in the medical press will name French pharma firm for failing to comply with disclosure rules
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PodcastChemistry World podcast - September 2014
We speak to Paul Clarke about the challenges of natural product synthesis and discuss the pros and cons of perovskite solar cells
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Business
Piramal exits drug discovery in India
Company will concentrate on generic medicines and clinical and contract research.
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ResearchExperimental Ebola drug 'impressive' in animal trials
All primates given ZMapp are cured of Ebola but the drug is still a long way from approval in humans
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