Medicinal chemistry – Page 65
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Business
First HIV drug approved as prevention
Truvada tablets can reduce the risk of infection for an HIV-negative person
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FeatureDrawing on drugs to kick the habit
While pharma companies stand accused of giving up on drugs to help people stop smoking, tobacco firms are looking at controversial nicotine replacement products. Anthony King surveys an area that is problematic on all sides.
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Business
GSK drug shines in HIV trial
HIV–Aids drug candidate dolutegravir outperformed Atripla tablets in Phase III
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OpinionSilicone safety: the status quo
Public alarm over the use of silicone is unwarranted, says Alan Lansdown
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Business
Good signs for Merck & Co insomnia pill
Suvorexant switches off wakefulness to help patients drop off quicker and stay asleep longer
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Business
More testing needed for ridaforolimus
Marketing approval for anti-cancer drug ridaforolimus has been held up in the US
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OpinionPeace, love and understanding
Chemists and biologists often view the process of drug discovery very differently
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News€224 million EU antibiotics initiative launched
The project will bring together the pharmaceutical industry and academia, but some institutes have reservations
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Opinion21st century toxicology
Thomas Hartung discusses the next generation of toxicity testing and the regulatory science of the future
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BusinessHDL drug class struggling after latest flop
The failure of another ‘good’ cholesterol-raising drug and a new genetic study casts shadow over HDL hypothesis
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News
Non-animal testing
L’Oréal has joined the US EPA to help develop alternatives to animal toxicity tests
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NewsVoluntary controls on antibiotics on US farms criticised
The US Food and Drug Administration has introduced guidelines to try to cut antibiotic use in livestock
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Feature
Making light work
Could light prove to be the ultimate weapon in the battle against deadly superbugs?
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Business
PCSK9 inhibitors against cholesterol problems perform well
Sanofi has reported Phase II data for a new drug candidate for lowering cholesterol levels in patients already taking statins
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News
Diabetes reduces antioxidant benefits
Raised glucose levels in diabetics may prevent important nutrients getting to tissues