New method uses gold nanoprobes to overcome the problems of PCR detecting small nucleic acids
The polymerase chain reaction (PCR) is the way to go if you want to detect small amounts of nucleic acids like DNA. But this technique requires expensive reagents, complex instruments and a repetitive amplification process. Now, Korean chemists have come up with a new way to detect ultra-small amounts of DNA. They call it associating and dissociating nanodimer analysis or, simply, ADNA.