Firms spar over single-molecule gene sequencing technology
Gene sequencing firm Pacific Biosciences is suing rival Oxford Nanopore Technologies for patent infringement, after successfully filing a broad patent on nanopore sequencing technology.
PacBio claims that Oxford Nanopore’s MinIon and PromethIon sequencers – which use protein-based pores to electrically read nucleic acid sequences – infringe US patent 9546400, granted to PacBio in January 2017. PacBio’s own sequencers employits Single Molecule Real Time (SMRT) sequencing technology, in which sequences are determined by synthesising complementary DNA strands inside nanosized ‘waveguide’ wells.