All Psychoactive articles
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NewsExplainer: nitazenes and xylazine – a cause for concern
Why is the use of these highly potent synthetic drugs rising dramatically?
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BusinessPositive trial sets stage for therapeutic use of MDMA in US
Hallucinogen-assisted psychiatric treatment heads to regulators, amid cost and other concerns
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NewsAustralia greenlights psychedelics for depression while UK research falls further behind
MDMA and psilocybin are to be offered to be patients suffering from intractable mental health conditions
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ResearchLipophilicity helps explain psychedelic drugs’ therapeutic effects
Understanding why psychedelic drugs that bind to serotonin receptors promote neuron growth, while serotonin itself does not
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ResearchFox urine compound as good as catnip for some felines
Dihydroactinidiolide is the first example of a compound excreted by a mammal that can elicit a catnip response
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ResearchChemists tame shamanic addiction treatment
Animal experiments show modified structures remove ibogaine’s hallucinogenic and heart-harming effects
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PodcastDMT – Dimethyltryptamine
Georgia Mills investigates the psychoactive found in ayahuasca that may mirror near-death experiences
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Podcast2C psychedelics
A class of hallucinogenic phenethylamines, explored by the 'godfather of psychedelics' Alexander Shulgin and sadly implicated in a tragedy at a 2017 music festival
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ResearchThousand year-old fox snout bag held potent hallucinogens
Chemical analysis reveals ancient South Americans used mix of psychoactive substances in rituals
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PodcastMyristicin
The spice that gives your Christmas eggnog its distinctive taste and aroma is also a toxic narcotic that played an important role in international history
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ReviewHow to Change Your Mind: The New Science of Psychedelics
Journalist Michael Pollan’s 9th book is a fascinating history of psychedelic drugs.
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NewsNitrous oxide causes UK drug law confusion
Successful defences based on laughing gas’ medical uses follow prominent convictions that have resulted in a legal lottery
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ResearchCrystal structure lifts lid on LSD’s secrets
Structure of hallucinogen bound to a human serotonin receptor could explain LSD’s potent and long-lasting effects
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PodcastErgotamine
Ben Valsler finds out why writing Alice’s adventures in Wonderland was such a headache for Lewis Carroll
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ResearchCatching up with legal highs
How do you test for drugs when you don’t know what you’re looking for?
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NewsNew law on legal highs approved in UK
A blanket ban on New Psychoactive Substances has been given final approval and will come into force in April
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ResearchCracking cocaine’s secret to sneaking into the brain
Researchers look to psychoactive substances for tips on drug development
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PodcastBarbituric acid
It may have been largely superceded in the clinic but Phil Robinson discovers there is no rest yet for barbituric acid