All Total synthesis articles
View all stories with this category.
-
-
Research
Streamlined synthesis of quinine showcases sustainable organic strategy
Five pot synthesis delivers highest yield of antimalarial to date
-
Research
Chirality-flipping reaction could completely change total synthesis strategies
Photocatalytic reaction that inverts configuration of chiral carbon centres offers new stereochemical editing logic
-
Research
Controversy surrounds corrected chemical structures
Researchers used machine learning-powered NMR prediction to correct improbable structures – but some of their revisions have been challenged
-
-
-
Opinion
Catalogues of complexity
The tangled web of fine chemicals supply frequently throws up surprises
-
Opinion
Exit strategy
Overcoming a major setback showed Derek Lowe could make it through graduate school
-
-
-
-
-
-
Opinion
Fully automated synthesis of fluorine-18 PET tracers
Making radioisotopes suitable for positron emission tomography
-
-
-
Opinion
Theodora Greene’s protecting groups
Katrina Krämer uncovers the woman behind the book on every organic chemist’s shelf
-
Research
Chemists complete synthesis of molecule ‘at the limits of complexity’
Synthesis of canataxpropellane paves the way to biological studies
-
Research
‘Inside-out’ chirality discovered by chance could have been missed in many molecules
A structure assignment odyssey finds a natural product with a type of isomerism never before seen in small molecules
-
Research
Program finds 5 million synthetic routes to complex chemicals
Only around five hundred ‘tactical combinations’ for advanced organic synthesis existed – until Chematica was let loose on the problem
