Total synthesis – Page 4
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ResearchHow total synthesis is creating antibiotics
Macrolide synthesis could reinvigorate the antibiotic pipeline
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Opinion(+)-Zincophorin methyl ester
New and old reactions combine for an elegant and concise synthesis
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ResearchTamed radicals expand chemical space
A method to functionalise complex molecules with catalytic radicals could expand chemical libraries of the drug and agrochemical industry
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ResearchBatch and flow: united at last
Fully automated reactor can carry out multistep reactions using both batch and flow chemistry
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OpinionHome synthesis is here – we must guide it
On-demand chemistry raises as many questions as it answers
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Opinion6-epi-Ophiobolin N
When it comes to cascade reactions, radicals are king of the ring-formers
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ResearchArduous natural product quest's unwelcome end
Thousands of experiments help find conditions to make (–)-maoecrystal V
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ResearchChemists hit a top synthetic target with pyramidal compounds
Non-classical covalent pyramidanes surprise with high bonding ionicity
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FeatureOrganic odysseys
Andy Extance looks at two drugs that cranked the synthetic challenge all the way up to Halaven
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ResearchChemistry's toughest total synthesis challenge put on hold by lack of funds
‘Seemingly impossible’ synthesis of highly potent poison maitotoxin nears completion after eight years
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FeatureUnpicking natural product synthesis
Is total synthesis in danger of a decline? Nina Notman investigates
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PodcastChemistry World podcast - May 2014
We speak to the ‘sultan of synthesis’, Phil Baran, and Peter James explains how labs can save cash on energy bills
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FeatureThe sultan of synthesis
Phil Baran is spurring organic chemists to rethink how they make complex compounds, as Mark Peplow discovers
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OpinionGone to completion
After a 66-step journey, Paul Docherty ponders the future of total synthesis in his final column
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OpinionMarcfortines B & C
Paul Docherty ponders a tasty cheeseboard as a source of synthetic inspiration
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