Total synthesis – Page 4
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Research
Arduous natural product quest's unwelcome end
Thousands of experiments help find conditions to make (–)-maoecrystal V
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Research
Chemists hit a top synthetic target with pyramidal compounds
Non-classical covalent pyramidanes surprise with high bonding ionicity
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Feature
Organic odysseys
Andy Extance looks at two drugs that cranked the synthetic challenge all the way up to Halaven
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Research
Chemistry's toughest total synthesis challenge put on hold by lack of funds
‘Seemingly impossible’ synthesis of highly potent poison maitotoxin nears completion after eight years
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Feature
Unpicking natural product synthesis
Is total synthesis in danger of a decline? Nina Notman investigates
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Podcast
Chemistry World podcast - May 2014
We speak to the ‘sultan of synthesis’, Phil Baran, and Peter James explains how labs can save cash on energy bills
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Feature
The sultan of synthesis
Phil Baran is spurring organic chemists to rethink how they make complex compounds, as Mark Peplow discovers
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Opinion
Gone to completion
After a 66-step journey, Paul Docherty ponders the future of total synthesis in his final column
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Opinion
Marcfortines B & C
Paul Docherty ponders a tasty cheeseboard as a source of synthetic inspiration
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Opinion
An 'Aye' for details
Small steps by synthetic chemists could mean giant leaps for those who follow, says Karl Collins
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Opinion
Pactamycin
Labelling a molecule 'inaccessible to synthesis' is a red rag to a bull, says Paul Docherty