All Gene therapy articles
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BusinessSarepta gene therapy deaths highlight tragic rare disease dilemma
Regulators block Duchenne muscular dystrophy treatment after fatal side-effects outweigh questionable efficacy
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BusinessUK becomes first country in the world to authorise a Crispr-based gene therapy
Treatment aims to cure patients with β-thalassaemia and sickle-cell disease
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ResearchGene therapy jab offers cheap and safe way to sterilise stray cats
Treatment could help to tackle populations of feral cats that threaten wildlife
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ResearchGene therapy showcases technique to extend life in mice
Lab mice lived significantly longer after receiving one of two genes, delivered using a mouse herpes virus
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OpinionWhen regulatory cooperation goes too far, we all lose
Were FDA staff unduly influenced by Biogen in approving Alzheimer’s antibody?
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ResearchMethod to make unusual oligonucleotides could be a boon for gene therapy drugs
Synthesis can insert unusual linkages into DNA molecules while rivalling industry standard chemistry in speed and efficiency
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BusinessPharmaceuticals roundup 2019
Under the shadow of political turmoil and major lawsuits, the industry returned to its strengths – making new drugs, and finding new ways to do it better
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OpinionWill Novartis's data manipulation damage relations with regulators?
Trust between the two has been compromised
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NewsData manipulation casts shadows on Novartis gene therapy
Manufacturing problems with other new medicines highlight difficulty of developing advanced treatments
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ResearchCrispr treatment reverses muscular dystrophy in mice
Upregulated gene triggers laminin-α1 protein production, reviving paralysed limbs
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OpinionIs this a golden age of new drug classes?
A host of new treatment modes are hitting the clinic and the market
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NewsPersonalised medicine has failed to live up to the hype, researchers claim
Predictions that Human Genome Project would usher in an era of tailored therapies have largely failed to come true
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FeatureThe quest to cure HIV
Although HIV–Aids can now be managed quite well with antiretroviral drugs, there is still no cure. Anthony King talks to the scientists trying to find one
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BusinessUS approves first RNA interference drug
Alnylam’s Onpattro (patisiran) can treat a rare hereditary disease by silencing a specific gene
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BusinessGene therapy gathers pace
Sarah Houlton charts the evolution, challenges and opportunities of cell and gene therapy
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BusinessNovartis’ $8.7bn AveXis deal shows gene therapy appeal
Acquisition indicates the value of potentially permanent cures for inherited diseases
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ReviewA crack in creation: the new power to control evolution
How studying bacterial immunity led to the development of Crispr
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FeatureDelivering gene therapy
After some well-publicised problems, gene therapy – delivering DNA into people’s cells using viruses – is booming, Anthony King finds
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ResearchDNA suitcases packed with gene therapy cargo
Nano-sized capsules can be unlocked to release drugs on demand