All Painkillers articles
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ResearchMorphine analogues kill pain with fewer negative side effects
Redesign of the potent painkiller’s core prevents breathing suppression and reduces addiction-related behaviours in mice
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BusinessNew type of painkiller approved in US
Sodium channel blocker prevents nerves transmitting pain signals
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ResearchBiochemical secrets of tarantula’s painful bite could point to perfect painkillers
King baboon spider venom could help scientists develop potent analgesics
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NewsParacetamol, ibuprofen and other painkillers may harm those suffering from chronic pain
Opioids and benzodiazepines should also be avoided in favour of non-drug therapies for treating chronic pain, recommends UK clinical practice body
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PodcastOxycodone and hydrocodone
Frances Addison examines how our quest to control and manage pain has led to a modern medical crisis, as opioids oxycodone and hydrocodone are among the most abused prescription medications in the US
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BusinessLandmark ruling in Oklahoma opioid lawsuit
J&J judged responsible for ‘public nuisance’ in first case to go to trial
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BusinessEmerging from the US opioid crisis
With litigation against suppliers in full swing, how does the US counter its addiction to powerful painkillers?
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FeatureFrom venoms to medicine
Venoms are a treasure trove of peptides that may provide a bounty of novel painkillers
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BusinessFDA asks Endo to take pain drug off market
Request part of larger strategy to address opioid misuse in the US
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NewsAnalytical test strip fights fentanyl overdoses
Simple chemical analysis helps drug users prevent overdosing on deadly opioid
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ResearchEdible MOF sugar-coats painkiller
When ibuprofen is encapsulated in a sugar-based MOF its effects last twice as long
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FeatureNew opioid drugs
Creating powerful new painkillers is a constant battle against side-effects – particularly addictions. James Mitchell Crow reports
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BusinessEndo drops opioid painkiller rights and cuts US sales force
375 staff to go as Endo says its established pain drugs ‘no longer require field promotion’
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PodcastHaloperidol
It failed as a painkiller, but Haldol rapidly became an essential medicine for schizophrenia. Raychelle Burks explains more
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ResearchBiotech breakthrough as yeast makes painkillers from sugar
Yields are still tiny but hopes are high that it could cut production costs
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PodcastDesomorphine
From potential painkiller to kitchen-cooked heroin replacement, Nate Adams tracks the history of desomorphine