All proteins articles
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ResearchAI method makes designer binders for ‘undruggable’ proteins
Technique can create molecules that target disordered regions of proteins and peptides
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ResearchDesigner protein switches conformations like a natural one
Researchers design, produce and test a synthetic protein with a dynamic structure
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ResearchAI takes step towards cracking biology’s toughest problem – protein sequencing
The team hopes the system will eventually be as influential as AlphaFold was for protein structure prediction
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ResearchDesigner protein performs multi-step catalysis with life-like performance
Computer-designed enzyme competitive with nature for the first time
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ResearchDesigner proteins to treat deadly snake bites could save thousands of lives
Small proteins can help to tackle some of the deadliest components of cobras and mambas
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ResearchDebunked dogma: disordered proteins disregard ligands’ chirality
Understanding unfolded proteins could boost drug discovery and decipher origins of life mysteries
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ResearchMechanochemistry can extract edible proteins from moor grass
Milder method to ‘recover the goodies that are within the grass’
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ResearchProteins with multiple structures open up AlphaFold’s black box
AI prediction model often fails to identify fold-switching, helping show how it works and the limits of its usefulness
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ResearchNanopore proteins designed from scratch and turned into biosensors
Artificial ion channels used to detect disease indicators and pharmaceuticals
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ResearchFirst regular molecular fractal in nature
Scientists have identified a protein that has a fractal structure and find that it was simply an evolutionary accident
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ResearchAlgorithm designs proteins from scratch that can bind drugs and small molecules
Strategy could stop an overdose or produce an antidote to a poison
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ResearchD-trypsin synthesis enables sequencing of mirror-image proteins
Reversing the chirality of a protein-digesting enzyme could aid the development of mirror-image therapeutics
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ResearchProtein folding stability set to be unravelled on a massive scale
Technique can analyse a million protein sequences at a time to provide data for machine learning models
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OpinionProtein filaments allow ‘diary’ of cell events to be read
Expression recording islands show when and where cells responded
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ResearchRedox flow batteries charge up with peptide-based electrolytes
Study shows how electrolytes could be degraded using acid and heat
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ResearchUnusual hydrogen bonds found in proteins help them bind their targets
Weak interactions between hydrogen and carbon atoms have synthetic chemistry implications
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BusinessFully synthetic proteins make tailored medicines
Bright Peak Therapeutics makes modified protein drugs from scratch
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ResearchOverreliance on cryocooled protein structures may compromise computational structure-based drug design
Scientists behind first of its kind study encourage more researchers to analyse protein structures at room temperature
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ResearchProtein-shaped sweets help students understand complex molecular structures
Edible protein models that can be identified by mouth could make chemistry education more inclusive to blind and visually impaired students
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OpinionFree radicals for post-translational modification
A technique for forming new carbon–carbon bonds at specific sites in proteins