All articles by Chris Nawrat

Opinion

(–)-Bipolarolide D

2024-06-12T08:30:00Z

A rare example of a [6 + 2]-cycloaddition

Opinion

(+)-Heilonine

2024-02-28T09:34:00Z

A short route that brings together the classical and cutting-edge

Opinion

(+)-iso-Phomopsene (and friends)

2023-09-26T13:30:00Z

A non-obvious combination unleashes the power of electrocyclisation

Opinion

(+)-KB343

2023-06-28T08:31:00Z

A total synthesis that uses a cunning trick to negotiate nitrogen

Opinion

(–)-Quinine

2023-02-01T09:44:00Z

Stop counting steps and move on to some one-pot reactions

Opinion

(–)-Tetrodotoxin

2022-10-12T08:40:00Z

Choosing an efficient route to a classic target

Opinion

Bastimolide B

2022-06-23T13:32:00Z

Fewer steps with boron chemistry

Opinion

(+)-Quassin

2022-02-25T14:19:00Z

A rare modern-day sighting of a quinone intermediate

Opinion

(+)-Njaoamine I

2021-11-04T14:30:00Z

Ringing in the advantages of alkyne methathesis

Opinion

(–)-Norzoanthamine

2021-06-30T08:34:00Z

A synthesis combining radical methods old and new

Opinion

Euonyminol

2021-02-18T14:31:00Z

Overcoming the challenges of working with highly polar molecules

Opinion

(+)-Vancomycin aglycon

2020-10-22T13:23:00Z

Optimising for efficiency deserves credit too

Opinion

(–)-Taxol

2020-06-25T13:41:00Z

Following nature’s lead

Opinion

(–)-Curvulamine

2020-02-25T14:56:00Z

Working through the Pains of pyrrole

Opinion

(±)-Rhabdastrellic acid A

2019-10-31T14:29:00Z

A triterpene that looks innocuous until it reveals the highly strained conformation of its rings

Opinion

(+)-Microladallene B

2019-06-21T09:27:00Z

A weird structure is enough to spark chemists’ interest, even without any obvious use

Opinion

Jorunnamycin A

2019-03-05T14:27:00Z

Sometimes synthetic ingenuity can trump nature

Opinion

(−)-Gelsemoxonine

2018-10-23T14:27:00Z

Harnessing the power of the nitro group

Opinion

Hosieine A

2018-06-27T12:12:00Z

In defence of name calling

Opinion

(–)-Callyspongiolide

2018-02-14T11:00:00Z

Ringing the changes with some unconventional chemistry