Tandem mass spectrometry method can distinguish lipid isomers
Researchers have developed a tandem mass spectrometry-based workflow capable of characterising and quantifying phosphatidylcholines, a major class of mammalian lipids. Previously, this task has involved complex instrumental set-ups or chemistry. Now, scientists have found a way to achieve the same goal using only standard instruments by adding ammonium bicarbonate into the lipid mixture.