Lilly pushes continuous drug production limits

Photograph of continuous crystallizers during processing

Source: © Eli Lilly and Company

Integrated flow synthesis and purification process for prexasertib meets high industry standards

Eli Lilly has taken an important step away from traditional batch-process drug manufacturing by using an industry-first continuous process to make a compound for phase I and II clinical trials. Workers at Lilly’s Kinsale site in Ireland, did three steps involved in producing cancer drug candidate prexasertib continuously, under current good manufacturing practice (CGMP) standards that ensure safety for human consumption.