Molecular pendulum sensors could track and monitor disease

A close-up photo of some blood samples in a lab

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DNA–antibody probes can detect specific proteins inside a live subject

Reagentless electrochemical sensors that use molecular pendulums to detect protein biomarkers could lead to wearable, ingestible and implantable devices for personalised tracking and monitoring of many diseases.

Biosensors are widely used for biomedical diagnosis and monitoring. Most use reagents in order to detect chemical reactions with target molecules. However, reagents add complexity, time and work for such tests. Moreover, sensors that require reagents cannot make in vivo measurements.