Nanopore sensor can detect individual volatile organic compounds

Man breathing out

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Technology could be used to detect subtle shifts in bodily markers in breath that herald infections and cancers

Scientists have developed a nanopore-based technology capable of detecting single molecules in real time – a major step toward fast, low-cost chemical profiling. Using engineered protein pores, the new approach targets aldehydes by briefly binding them inside nanoscale channels, and creating distinct electrical signals that reveal their chemical identity and abundance.