‘New era’ of designer proteins for medicines and materials

Designing proteins HHH rd3 0138

Source: Science/AAAS

Platform computed thousands of stable designs for short proteins, up from two previous designs

The design and discovery of stable non-natural proteins, which could have far-reaching applications from medicines to materials, has entered a ‘new era’ thanks to a faster technique developed by researchers in the US and Canada. Combining computational design with advances in large-scale gene synthesis and high throughput screening, the team was able to identify thousands of synthetic mini-proteins.