All RNA articles – Page 2
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BusinessRNA vaccines are coronavirus frontrunners
Several groups have potential Sars-CoV-2 vaccines ready or close to testing, thanks to rapid development pathways
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ResearchUnified synthesis shows how genetic alphabet could have been put together on early Earth
Cycles of wet and then dry conditions provide the right conditions to make all the nucleobases from basic chemicals
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ResearchMineral surfaces promoted variation in prebiotic RNA
Thermodynamic model probes the entropic cost of enriching RNA strands adsorbed on a surface
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ResearchHepatitis C drug lead designed to target virus RNA
Gene-to-RNA-to-medicine pipeline possible thanks to technique that reveals interactions between RNA and small molecules
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ResearchScrutiny of SmartFlares raises questions over RNA probes
Merck Millipore technology for detecting specific RNAs may not live up to claims
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BusinessLilly and CureVac to collaborate on mRNA cancer vaccines
Deal could see CureVac net up to $1.8 billion in upfront and milestone payments
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ResearchCrispr gene editor can now alter RNA as well as DNA
Gene editing technique is developing apace with two new technologies unveiled
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OpinionRise of the biologics
Antibodies, RNA and gene therapy don’t necessarily compete with small molecule drugs – and they all rely on chemistry
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BusinessSilence Therapeutics and Alnylam in patent dispute
Suit alleges competitors need to license Silence patents relating to their drug cantidates
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ResearchGooey origins for RNA world
Viscous muddy pond edges may have been incubators for the rise of self-replicating RNAs on ancient Earth
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ResearchNucleic acid instability challenges RNA world hypothesis
Early life may have contained both RNA and DNA, rather than just RNA
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OpinionHow game theory could explain complex life
Philip Ball asks if the building blocks of life benefit from cooperation
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ResearchAdenine and guanine synthesised using prebiotic pathway
Two of the nucleotide bases that make up genetic material have been formed in early Earth simulation experiments
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ResearchBroken ribozyme comes to life
Low temperatures on early Earth may have helped RNA world organisms emerge
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ResearchBuilding blocks of life made in space ice simulations
Complex sugars – including the ‘backbone’ of RNA – have been created in lab-made interstellar ice
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ResearchLifting molecular brake may have kept primeval cells running
Removing RNA restriction can steady biochemical function, with relevance for life’s emergence
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NewsPressure on controversial nanoparticle paper builds
Expression of concern and reprimand for chemists may seal fate of work on palladium particles
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ResearchPeptide glue may have held first protocell components together
Association between RNA and primitive membranes 4 billion years ago thought to have kick-started life could have been mediated by peptides
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ResearchAncient RNA enzymes formed from freeze-thaw cycles
Temperature cycles help small pieces of RNA assemble into complex ribozymes
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