All synthetic chemistry articles
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ResearchFilter paper simplifies squaramide synthesis
Capillary-driven flow distributes reagents evenly
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ResearchSpray-drying investigated as a speedy method for synthesising small organic molecules
Technique applied to Schiff-base condensations, Claisen–Schmidt reactions and amine acylations
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ResearchSkeletal editing targets double bonds
Two new techniques selectively install nitrogen atoms into complex molecules
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ResearchStudy challenges notion that solution-phase organic reactions are unfeasible at high temperatures
Capillary synthesis at 500°C converts N-substituted pyrazoles into their isomers within five minutes
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ResearchCross-coupling technique cracks open alcohols for chemical synthesis
A new alcohol–alcohol cross coupling reaction could become a powerful new tool for synthetic chemists
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ResearchHydrogen-free hydrogenation offers simple solution for medicinal chemists
New method expands electrochemical hydrogenation’s scope
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OpinionAre elemental analysis guidelines appropriate?
The standard journal requirement of ±0.4% for carbon, hydrogen and nitrogen is not statistically sound
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ResearchRobot chemist snaps 3D building blocks together like Lego to make complex molecules
Automated synthesiser uses a new class of boronates that are a thousand times more stable than those previously used
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WebinarUsing flow chemistry to give early drug discovery processes a boost
Discover how pioneering modular flow chemistry technologies can unlock the potential for discovery chemists to accelerate research
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WebinarThe age of digital chemistry
Join us to learn how data can solve existing bottlenecks in synthetic chemistry and why data analysis demands a multidisciplinary approach
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ResearchAutomated organic synthesis made easier with capsule-based console
Integrated console to synthesise drug-like molecules requires minimal user input
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ArticleNew frontiers in synthetic chemistry conference
An accomplished lineup of speakers will present at the New frontiers in synthetic chemistry conference co-hosted by AstraZeneca and the Royal Society of Chemistry in November
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OpinionChemists amid coronavirus: Martyn Coles
In New Zealand, where there are close to zero active cases of Covid-19, labs have reopened with no distancing rules
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ResearchNanodroplet encapsulation technique crystallises the ‘uncrystallisable’
High-throughput method that uses mere micrograms of small molecule samples could ease frustration for crystallographers
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OpinionTaking benzyl fluorides beyond game changing reports
Decarboxylative cross-coupling to produce benzyl fluorides
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ArticleAstraZeneca conference – New frontiers in synthetic chemistry
Academia and industry meet to solve the challenges of modern drug discovery and process chemistry
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OpinionWhy synthetic organic chemistry is the ultimate creative process
Dylan Stiles explains why he loves to go skydiving in a lab coat