Medicine and health
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Research
New mechanism identified that is potentially linked to very early stages of Alzheimer’s
Understanding role of fragments of amyloid protein could lead to novel therapies for the disease
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Research
Could mechanochemistry have saved Abbott Laboratories $250 million?
Ball milling solves problem of disappearing ritonavir polymorph
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Research
Certain household chemicals could pose a threat to brain health, research suggests
Cell and animal tests suggest two classes of common chemicals might play a role in neurological disease
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Research
Cross-coupling technique cracks open alcohols for chemical synthesis
A new alcohol–alcohol cross coupling reaction could become a powerful new tool for synthetic chemists
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Research
Non-antibiotics with antibacterial activity could help in the fight against antimicrobial resistance
New analysis shows that non-antibiotic drugs kill bacteria through mechanisms that differ from those of conventional antibiotics
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Research
Classic cross-coupling reactions rerouted to make new products
Combination of Suzuki–Miyaura and Buchwald–Hartwig couplings produces carbon–nitrogen–carbon linked compounds
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Research
Pre-organising antibiotic structure could aid fight against resistance
Strategy that produced new antibiotic could allow researchers to repurpose existing antibiotics
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Research
Heavy metals are potential ovarian toxicants
Exposure to metals like arsenic, cadmium and mercury linked to reduced egg production, earlier menopause for middle-aged women
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Research
Rare medical transmission of Alzheimer’s disease from donor to patient discovered
Human growth hormone extracted from cadavers passed disease protein to at least five people
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Research
Unravelling enzyme pathway of Taxol precursor brings synthetic production of cancer medicine closer
Expression of nine genes in tobacco plants led to formation of complex precursor of drug
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Research
Steroid separation made easy with photoswitchable coordination cage
Light-activated coordination cage purifies progesterone
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Research
PFAS linked to foetal metabolism disorders
‘Forever chemicals’ in the livers of unborn children can alter lipid metabolism and may increase the risk of metabolic disease in adulthood
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Research
D-trypsin synthesis enables sequencing of mirror-image proteins
Reversing the chirality of a protein-digesting enzyme could aid the development of mirror-image therapeutics
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Research
Machine learning identifies promising antibacterial ruthenium-based drug candidates
Algorithm demonstrated a success rate six times higher than a random screening against resistant bacteria
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Research
Biocatalysis breakthrough enables synthesis of lactam building blocks for drugs
Enzymatic cyclisation of oxazolone reagents offers a cheap and simple route to important antibiotic precursor
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Research
Nanopore test could identify misfolded proteins in Alzheimer’s and Parkinson’s disease
Sensor could provide more accurate diagnoses and help doctors track progress of neurodegenerative diseases
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Research
Antibiotic adjuvant designed to subvert bacterial defence mechanisms
Amphiphilic molecule helps obsolete antibiotics accumulate and act within bacteria
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Research
New insights into polyamorphism could influence how drugs are formulated
Findings suggest dihedral angle distribution might explain why polyamorphs have different physical properties
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Research
Insulin medicines more resilient to temperature than previously thought
Review suggests more lenient storage guidelines could make diabetes treatments more accessible
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Research
Underwater device reveals marine chemical diversity
I-Smel device probes metabolites produced by Mediterranean sponges