All proteins articles
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ResearchAlgorithm designs proteins from scratch that can bind drugs and small molecules
Strategy could stop an overdose or produce an antidote to a poison
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ResearchD-trypsin synthesis enables sequencing of mirror-image proteins
Reversing the chirality of a protein-digesting enzyme could aid the development of mirror-image therapeutics
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ResearchProtein folding stability set to be unravelled on a massive scale
Technique can analyse a million protein sequences at a time to provide data for machine learning models
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OpinionProtein filaments allow ‘diary’ of cell events to be read
Expression recording islands show when and where cells responded
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ResearchRedox flow batteries charge up with peptide-based electrolytes
Study shows how electrolytes could be degraded using acid and heat
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ResearchUnusual hydrogen bonds found in proteins help them bind their targets
Weak interactions between hydrogen and carbon atoms have synthetic chemistry implications
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BusinessFully synthetic proteins make tailored medicines
Bright Peak Therapeutics makes modified protein drugs from scratch
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ResearchOverreliance on cryocooled protein structures may compromise computational structure-based drug design
Scientists behind first of its kind study encourage more researchers to analyse protein structures at room temperature
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ResearchProtein-shaped sweets help students understand complex molecular structures
Edible protein models that can be identified by mouth could make chemistry education more inclusive to blind and visually impaired students
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OpinionFree radicals for post-translational modification
A technique for forming new carbon–carbon bonds at specific sites in proteins
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ResearchMolecular pendulum sensors could track and monitor disease
DNA–antibody probes can detect specific proteins inside a live subject
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OpinionBehind the screens of AlphaFold
Predicting protein structure doesn’t necessarily say much about function
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FeatureEngineering a handshake for proteins
Once considered undruggable, chemists are beginning to grasp protein–protein interactions, according to Ian Le Guillou
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BusinessRosa Biotech gets biosensors on the nose
Protein barrel arrays mimic mammals’ olfactory system to distinguish many different molecules
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ResearchProteins pinpointed in cells at nanometre resolution
Combining fluorescence microscopy and electron tomography will reveal more about how cells work and how diseases disrupt them
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ResearchDNA instructions pack proteins into unique crystal structures
Process could aid discovery of materials that exploit specific protein functions, such as drug molecules or biocatalysts
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Research‘Chemical ear defenders’ could prevent hearing loss
Discovery of receptor connected to hearing loss has led to a chemical compound that can protect the neuromechanical machinery in mice’s ears
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OpinionThe chemical absurdity of molecular recognition
Many biological models rely on an agency that molecules lack
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ResearchBiodegradable batteries could be made from modified proteins
Coiled polypeptides modified with redox-active molecules make for eco-friendly single-use batteries