The evolving landscape of pain drug discovery

For most of us, pain is an unwelcome but vital warning system that tells us when something is wrong. However, for the small number of people living with congenital insensitivity to pain (CIP), a serious and debilitating rare condition, that warning system is entirely absent. Those with CIP may bite through their tongues, fracture bones without realising and face life-threatening injuries from hazards the rest of us instinctively avoid.