HPLC alternative purifies peptide cocktails in record time

An illustration showing a dishwasher for molecules

Source: © M Eugenio Vazquez

Reductively cleavable brominated peptide linker unlocks contamination-free traceless release from solid support

Scientists have developed a method for purifying large numbers of peptides in a parallel fashion. It uses a cleavable linker system and releases unprotected peptides. The team hope to develop the concept into a routine tool that can keep pace with the increasingly high output of parallel peptide synthesis.