All peptides articles
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ResearchPeptide tags that encode chemical libraries could revolutionise drug discovery
Simple strings of amino acids store over 4 gigabits of data, offering a highly stable solution for screening small molecule libraries
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Research
AI beats human experts when it comes to peptide design
Algorithm throws up some counter-intuitive structures in contest
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Opinion
Cracking codons
Understanding how chemistry links RNA triplets to the properties of amino acids
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Research
Tripeptide catalyst that creates carbon–carbon bonds works in milk, beer and cell lysates
Study sparks excitement by showing a short-chain peptide can be a potent catalyst in numerous complex environments
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Research
Glassware found to promote reactions in Miller–Urey 'primordial soup' experiment
By running their famous 1952 experiment in glass flasks, Stanley Miller and Harold Urey might have unintentionally simulated the role of rocks on early Earth
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Research
Sortase A strategy could see ribosomal products reach further across chemical space
Compound libraries set to benefit from process that harnesses promiscuity of post-translation enzymes
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Research
Peptide ligation strategy unlocks diverse range of structural motifs
Approach expected to influence design of protein–protein interaction inhibitors
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Research
Machine learning tool sets out to find new antimicrobial peptides
IBM researchers say their fully automated AI-driven system could speed up the discovery of molecules for novel antibiotics
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Research
HPLC alternative purifies peptide cocktails in record time
Reductively cleavable brominated peptide linker unlocks contamination-free traceless release from solid support
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Research
Peptides self-assemble to support growth of artificial tumours
Cancer cells grown around bioengineered microfibres make an ideal model to test new chemotherapy drugs
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Research
Protein synthesis revolution on way as large peptides made in hours not days
Flow chemistry can now make peptide chains up to 164 amino acids long in one go
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Research
Why does all life use the same 20 amino acids?
Chemical properties offer an answer to why nature limits itself to so few protein building blocks
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Research
Rainproof pesticide uses sticky peptides to defend against Asian soybean rust
Devastating fungal disease tackled with antimicrobial and anchor peptide combo
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Research
New family of peptides from extremophile show antibiotic promise
Scientists isolate salinipeptins from a bacterium living in America’s Dead Sea
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Research
UV can introduce oxidation artefacts during protein purity tests
HPLC–UV–MS blamed for impurities spotted by AstraZeneca team
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Research
Venom peptides reveal secrets of scorpion evolution
The shapes of toxins found in venom are helping to resolve the scorpion’s family tree
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Research
New peptide destroys Zika virus in brain for first time
Engineered molecule ruptures virus particles to tackle infection
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Research
Nucleus infiltrated by peptide gene switch
Synthetic peptides used to control cellular processes
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Research
Natural and unnatural peptides team up to target Ebola
New method to hunt down protease-stabilised peptide inhibitors of large proteins
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Research
Plotting a course to new antibiotics
Mapping out the chemical space of peptide antibiotics offers an efficient way to find new compounds
