Tornado at Pfizer plant accentuates US drug shortage issues

Aerial image of a large white warehouse that has been flattened surrounded by debris and upturned containers

Source: © Travis Long/The News & Observe/AP/Alamy Stock Photo

Perennial problem will not be addressed without major reforms to drug market

On 20 July, a tornado tore through a Pfizer plant in Rocky Mount, US, destroying part of a large facility that makes sterile injectable drugs. The facility manufactures a quarter of Pfizer’s sterile injectables for US hospitals, comprising around 8% of total US consumption. 

An initial FDA analysis pinpointed fewer than 10 drugs for which the Rocky Mount plant is the sole source for the US market, with Pfizer itself outlining 12 products of concern. Nonetheless, the disruption caused alarm amongst drug purchasers because there are already hundreds of drugs listed as in short supply in the US.